Microglia Products
Microglia are often referred to as the "guardians" of the brain. They constantly monitor and adjust the brain's environment, responding to injury, infection, and inflammation. Their primary functions include the removal of debris, support of neurons, and regulation of neuroinflammation. A variety of recent research investigations have underscored the significant importance of microglial cells in the context of neurological diseases. At Creative Biolabs, we are committed to advancing neuroscience by offering premium microglia cell products specifically designed for researchers.
Product Overview
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Primary Microglia
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Immortalized Microglia
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Human iPSC-derived Microglia
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Applications
Microglia are essential for modulating neuroinflammatory responses, supporting neuronal health, and regulating synaptic connections. Microglia cell products have various applications in vitro research:
- Neuroinflammation Studies: Microglia serve as the primary immune responders in the central nervous system and play a crucial role in regulating neuroinflammation. Researchers can use these products to explore phagocytosis, inflammasome, cytokine release and NO/ROS release.
- Neurodevelopment: Microglia influence neuronal development and synaptic pruning. Exosomes and signaling molecules secreted by microglia aid in understanding their role during critical periods of brain development.
- Disease Modeling: Disease-derived or stimulus-induced microglial products can be utilized in generating in vitro models of diseases like Alzheimer's and multiple sclerosis, allowing for the investigation of disease mechanisms and potential therapeutic targets.
- Microglia Migration: I Microglia migration is crucial in research as it helps elucidate their role in brain development, immune response, and neurodegenerative diseases. Understanding their migration patterns can inform therapeutic strategies for conditions like Alzheimer's and multiple sclerosis, enhancing targeted treatments.
- Drug Discovery: Compounds that modulate microglial activity are being explored for neuroprotective effects. Screening for these compounds can lead to novel treatments for neurodegenerative disorders.
Features & Advantages
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Related Services
We are excited to offer you the following microglia-related services utilizing our microglia products.
| Primary Microglia | hiPSC-derived Microglia | Immortalized Microglia | Microglia Assay |
Reference
- Bull, Daniel et al. "Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood-Brain Barrier Integrity." Cells. 2022;11(3):419. Distributed under Open Access license CC BY 4.0 without modification.
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Fluorescent Immortalized Primary Cells
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Fluorescent Immortalized Primary Cells
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- 3D Cell Culture
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- 3D Cell Culture
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- Microglia
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- 3D Cell Culture
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- Microglia
HAPI Cell Culture Specialty Complete Medium
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- Microglia
BV2 Cell Culture Specialty Complete Medium
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N9 Cell Culture Specialty Complete Medium
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HMC3 Cell Culture Specialty Complete Medium
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- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
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- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
