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Creative Biolabs

Microglia Products

Microglia are often referred to as the "guardians" of the brain. They constantly monitor and adjust the brain's environment, responding to injury, infection, and inflammation. Their primary functions include the removal of debris, support of neurons, and regulation of neuroinflammation. A variety of recent research investigations have underscored the significant importance of microglial cells in the context of neurological diseases. At Creative Biolabs, we are committed to advancing neuroscience by offering premium microglia cell products specifically designed for researchers.

Product Overview Applications Features & Advantages Related Services Related Products

Product Overview

Fig.1 Primary mouse microglia (Creative Biolabs Original) Primary Microglia
Fig.2 Human Microglia HMC3 (Creative Biolabs Original) Immortalized Microglia
Fig 3 Immunofluorescence image of hiPSC-derived microglia. (Cibelli, 2021) Human iPSC-derived Microglia
  • iNeu™ Microglia
  • iNeu™ Human Microglia - Alzheimer's Disease
  • iNeu™ Human Microglia - Parkinson's Disease
  • iNeu™ Human Microglia - Epilepsy
  • iNeu™ Human Microglia - Autism Spectrum Disorder

Applications

Microglia are essential for modulating neuroinflammatory responses, supporting neuronal health, and regulating synaptic connections. Microglia cell products have various applications in vitro research:

  • Neuroinflammation Studies: Microglia serve as the primary immune responders in the central nervous system and play a crucial role in regulating neuroinflammation. Researchers can use these products to explore phagocytosis, inflammasome, cytokine release and NO/ROS release.
  • Neurodevelopment: Microglia influence neuronal development and synaptic pruning. Exosomes and signaling molecules secreted by microglia aid in understanding their role during critical periods of brain development.
  • Disease Modeling: Disease-derived or stimulus-induced microglial products can be utilized in generating in vitro models of diseases like Alzheimer's and multiple sclerosis, allowing for the investigation of disease mechanisms and potential therapeutic targets.
  • Microglia Migration: I Microglia migration is crucial in research as it helps elucidate their role in brain development, immune response, and neurodegenerative diseases. Understanding their migration patterns can inform therapeutic strategies for conditions like Alzheimer's and multiple sclerosis, enhancing targeted treatments.
  • Drug Discovery: Compounds that modulate microglial activity are being explored for neuroprotective effects. Screening for these compounds can lead to novel treatments for neurodegenerative disorders.

Features & Advantages

  • High purity and quality
  • Ready-to-ship
  • Specialty Complete Medium
  • Custom Products

Related Services

We are excited to offer you the following microglia-related services utilizing our microglia products.

Primary Microglia hiPSC-derived Microglia Immortalized Microglia Microglia Assay

Reference

  1. Bull, Daniel et al. "Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood-Brain Barrier Integrity." Cells. 2022;11(3):419. Distributed under Open Access license CC BY 4.0 without modification.
For Research Use Only. Not For Clinical Use.

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