Pluripotent Stem Cell Products
Pluripotent stem cells are cells that have the ability to self-renew and can divide and develop into the three main germ cell layers of an early embryo, thereby developing all cells of the body, but without extra-embryonic tissues (such as the placenta). Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are the two main types of pluripotent stem cells. There are currently two main methods of generating cells with multipotent properties. The first involves the isolation of internal cell masses from early human blastocysts and cultivation under appropriate culture conditions to produce human embryonic stem cells (hESCs). The second involves artificial expression of key developmental transcription factors in somatic cell types, which can reprogram cells into induced pluripotent stem cells (iPSCs) under appropriate culture conditions.
Cytokines for iPSC Generation
Unlike ES cells, iPS cells are ideal for treatment and research, and isolating them will not cause the same moral issues. Human iPS cells may be an ideal source for patient-specific therapies because they can be derived from the patient itself. In addition, iPS cells can also serve as useful research tools in the following ways: 1) human disease models for screening new drugs or studying pathogenesis and toxicology mechanisms, 2) for screening potential teratogens or for research, and 3) for understanding the tissue repair and regeneration.
In order to generate iPS cells, Creative Biolabs provides multiple key cytokines which play an important role in early development, for example, OCT-3 / 4, KLF-4, SOX2, c-MYC, and NANOG, which have proved to be essential for the specification of pluripotent stem cell identity.
Culture Products for hPSCs
Creative Biolabs iPSC archive includes well-characterized human/mouse iPS cell lines suitable for multiple uses, such as genome editing for disease models, differentiation into selected cell lineages, and drug toxicity / efficiency screening:
- Footprint-free iPSC cells and retrovirus-reprogrammed iPSC
- Characterized by pluripotency markers, karyotype and differentiation potential
- Provide more characterization options
- Multiple donor tissue sources are available: PBMC, fibroblasts, umbilical cord blood, fat cells in health and sick patients
- Tested by CRISPR genome editing and differentiation potential
- Can be used to construct engineered and / or differentiated isogenic cell lineages
Creative Biolabs also provides a series of research tools needed to study the function of PSCs. Our product portfolio includes cell lines from multiple species, optimized serum-free media, reliable cell differentiation media, media additives, and key cell markers and research antibodies.
Please browse the options below to take a deeper look at the tools you need for your research.
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Used to quickly and effectively differentiate human pluripotent stem cells into dorsal root ganglion-like NeuSensory neurons.
- Applications:
- Cell Differentiation
- Cell Types:
- Sensory Neuron; iPSC
Dulbecco's phosphate-buffered saline without calcium and magnesium
- Applications:
- Cell Culture
- Cell Types:
- iPSC; Embryonic Stem Cell; Neural Lineage Cell
Dulbecco's phosphate-buffered saline without calcium and magnesium
- Applications:
- Cell Culture
- Cell Types:
- iPSC; Embryonic Stem Cell; Neural Lineage Cell
Cell detachment solution
- Applications:
- Cell Dissociation
- Cell Types:
- iPSC; Embryonic Stem Cell; Neural Lineage Cell
Enzyme-free cell dissociation reagent
- Applications:
- Cell Dissociation
- Cell Types:
- iPSC; Embryonic Stem Cell; Neural Lineage Cell
5 x 6-well plates
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- Neural Lineage Cell
Rinsing solution for cultureware to prevent cell adhesion
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- Neural Lineage Cell
5 x 6-well plates
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- Neural Lineage Cell
6-well plate
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- Neural Lineage Cell
Kit includes 2 CultWell™ S8 6-well plates and a bottle of CultWell™ Rinsing Solution
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- Neural Lineage Cell
Animal component-free suspension culture medium for human ES and iPS cells
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- iPSC; Embryonic Stem Cell
Defined, feeder-free maintenance medium for human ES and iPS cells
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- iPSC; Embryonic Stem Cell
Serum-free media for suspension culture of human ES and iPS cells
- Applications:
- Cell Culture; Cell Expansion
- Cell Types:
- iPSC; Embryonic Stem Cell
Matrix for maintenance of human ES and iPS cells in combination with StemTes™ maintenance media
- Applications:
- Cell Culture; Cell Maintenance
- Cell Types:
- iPSC; Embryonic Stem Cell
Feeder-free and animal component-free reprogramming medium for human iPS cell induction
- Applications:
- Cell Culture; Cell Reprogramming
- Cell Types:
- iPSC
Defined, serum-free, xeno-free medium for pluripotent stem cells
- Applications:
- Cell Culture; Cell Differentiation
- Cell Types:
- iPSC; Embryonic Stem Cell
Defined, serum-free, xeno-free medium for pluripotent stem cells
- Applications:
- Cell Culture; Cell Differentiation
- Cell Types:
- iPSC; Embryonic Stem Cell
Xeno-free, defined, feeder-free medium for maintenance of undifferentiated human ES and iPS cells
- Applications:
- Cell Culture; Cell Maintenance
- Cell Types:
- iPSC; Embryonic Stem Cell
Feeder-free, animal component-free culture medium for maintenance of human ES and iPS cells
- Applications:
- Cell Culture; Cell Maintenance
- Cell Types:
- iPSC; Embryonic Stem Cell
Stabilized feeder-free maintenance medium for human ES and iPS cells
- Applications:
- Cell Culture; Cell Maintenance
- Cell Types:
- iPSC; Embryonic Stem Cell
Feeder-free maintenance medium for human ES and iPS cells, cGMP grade
- Applications:
- Cell Culture; Cell Maintenance
- Cell Types:
- iPSC; Embryonic Stem Cell
Low-insulin, animal component-free medium for the differentiation of human ES and iPS cells
- Applications:
- Cell Differentiation
- Cell Types:
- iPSC; Embryonic Stem Cell
For the generation of microglia from human ES and iPS cell-derived microglia precursors
- Applications:
- Cell Differentiation
- Cell Types:
- Microglia; iPSC
For differentiation of human ES or iPS cells into hematopoietic progenitor cells
- Applications:
- Cell Differentiation
- Cell Types:
- iPSC; Embryonic Stem Cell
For the generation of microglia precursors from human ES and iPS cell-derived hematopoietic progenitor cells
- Applications:
- Cell Differentiation
- Cell Types:
- Microglia; iPSC
For the differentiation of human ES and iPS cells to definitive endoderm.
- Applications:
- Cell Differentiation
- Cell Types:
- iPSC; Embryonic Stem Cell
For differentiation of human PSCs to cardiomyocytes and long-term maintenance of human PSC-derived cardiomyocytes
- Applications:
- Cell Differentiation
- Cell Types:
- iPSC; Embryonic Stem Cell
For thawing and culturing hPSC-derived cardiomyocytes
- Applications:
- Cell Culture
- Cell Types:
- iPSC; Embryonic Stem Cell
For dissociation of hPSC-derived cardiomyocytes
- Applications:
- Cell Dissociation
- Cell Types:
- iPSC; Embryonic Stem Cell
For long-term maintenance of human PSC-derived cardiomyocytes
- Applications:
- Cell Culture; Cell Maintenance
- Cell Types:
- iPSC; Embryonic Stem Cell
- NeuroMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody(NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2275) (Cat#: NRP-0422-P2275)
- NeuroMab™ Anti-CD32b Antibody(NRP-0422-P1803) (Cat#: NRP-0422-P1803)
- NeuroMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P517) (Cat#: NRP-0422-P517)
- NeuroMab™ Anti-CD20 Antibody(NRP-0422-P1230) (Cat#: NRP-0422-P1230)
- NeuroMab™ Anti-FGFR1 Antibody(NRP-0422-P1244) (Cat#: NRP-0422-P1244)
- NeuroMab™ Anti-pTau Antibody(NRP-0422-P1719) (Cat#: NRP-0422-P1719)
- NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P792) (Cat#: NRP-0422-P792)
- NeuroMab™ Anti-GD2 Antibody(NRZP-1222-ZP767) (Cat#: NRZP-1222-ZP767)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Rat Retinal Muller Cell Line, Immortalized (Cat#: NCL-21P6-192)
- Human Dental Pulp Stem Cells (Cat#: NRZP-1122-ZP113)
- iNeu™ Retinal Pigment Epithelial Cells (RPE) (Cat#: NRZP-0323-ZP92)
- iNeu™ Human Midbrain Dopaminergic Neurons (Cat#: NCL-21P6-003)
- Immortalized Human Cerebral Microvascular Endothelial Cells (Cat#: NCL-2108-P020)
- Green Fluorescent Tau SH-SY5Y cell Line (Cat#: NCL2110P219)
- Rat Immortalized Retinal Muller Cell Line rMC-1 (Cat#: NCL-2106-S93)
- iNeu™ Microglia (Cat#: NCL-7P018)
- Human Hippocampal Neuron Cells HPPNCs (Cat#: NCL2110P106)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- pAAV-EF1a-DIO-EGFP-WPRE (Cat#: NTA-2012AD-P285)
- Dextran-CYanine5.5 (Cat#: NTA-2011-ZP118)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA (Cat#: NTA-2010-TT342)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- AAV2/2Retro-CAG-DIO-EGFP-2A-TetTox-pA [Neural Tracing] (Cat#: NTA-2012-ZP303)
- rAAV-CAG-DIO-G-Flamp1 (Cat#: NRZP-0722-ZP719)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
