Brain Imaging Platform

Creative Biolabs has developed the high-speed fluorescence microscopy imaging system which is primarily designed to achieve high-precision and fast fluorescence imaging analysis of internal structures in biological tissues and clinical medical samples such as the brain, embryos, and pathological slices. It can be used for multi-channel imaging of different-sized samples, including mouse brains, macaque brains, and various tissue organs. It is suitable for rapid analysis of virus tracing, early gene expression analysis, and quick analysis of behavior-related neural circuits.

Fig.1 3D imaging of neural structures in intact tissues.¹

Key Features of our Brain Imaging Technology

• Whole-brain imaging of mice with a resolution of 0.5μm 0.5μm 3.5μm within two hours
• Imaging of thick tissue samples
• Multi-channel imaging of different-sized samples
• Suitable for mouse brains, tree shrew brains, marmoset brains, macaque brains, and even human brains
• Imaging speeds that are hundreds to thousands of times faster compared to confocal microscopy and two-photon fluorescence microscopy.

Highlights: More Output. More Possibilities. More Efficient.

Greater Readouts

3D imaging allows for a comprehensive understanding of the entire sample

Multi-Channel

Multi-channel imaging of different-sized samples

Faster Speed

Hundreds to thousands of times faster than confocal microscopy and two-photon fluorescence microscopy

Multi-Color

405nm, 488nm, 550nm, 647nm, etc. can be used for imaging

Unparalleled Resolution

Ultra-high resolutions to visualize the brain's microstructure and cellular organization with exceptional clarity.

High Signal Intensity

Ability to preserve strong fluorescence signals for multiple fluorescent proteins.

Applications

The versatility and precision of Creative Biolabs' Brain Imaging Platform make it applicable to a wide range of research areas in neuroscience. Some notable applications include:

Brain Tissue Imaging

Mouse brains, tree shrew brains, marmoset brains, macaque brains.

AI Pathological Analysis

High-precision and fast fluorescence imaging analysis of internal structures in pathological slices related to neurological disorders.

Neural Circuit Analysis

Fast analysis of tracing virus for rapid analysis of behavior-related neural circuits.

Neural Gene Profiling

Suitable for analyzing the expression of immediate-early genes in brain tissue.

With its high-resolution imaging capabilities, advanced data analysis algorithms, and integration with clinical studies, our platform provides researchers with a powerful tool to unravel the complexities of the human brain. For further information or to initiate a discussion regarding your unique requirements, please contact us today to explore the possibilities of collaborating with our company.

Reference

1. Zhu, Jingtan, et al. "MACS: rapid aqueous clearing system for 3D mapping of intact organs." Advanced Science 7.8 (2020): 1903185.