Brain Imaging Platform
Creative Biolabs has developed the high-speed fluorescence microscopy imaging system which is primarily designed to achieve high-precision and fast fluorescence imaging analysis of internal structures in biological tissues and clinical medical samples such as the brain, embryos, and pathological slices. It can be used for multi-channel imaging of different-sized samples, including mouse brains, macaque brains, and various tissue organs. It is suitable for rapid analysis of virus tracing, early gene expression analysis, and quick analysis of behavior-related neural circuits.
Fig.1 3D reconstruction and imaging of LSFM images.1
Key Features of our Brain Imaging Technology
- Whole-brain imaging of mice with a resolution of 0.5μm 0.5μm 3.5μm within two hours
- Imaging of thick tissue samples
- Multi-channel imaging of different-sized samples
- Suitable for mouse brains, tree shrew brains, marmoset brains, macaque brains, and even human brains
- Imaging speeds that are hundreds to thousands of times faster compared to confocal microscopy and two-photon fluorescence microscopy.
Highlights: More Output. More Possibilities. More Efficient.
Greater Readouts
3D imaging allows for a comprehensive understanding of the entire sample
Multi-Channel
Multi-channel imaging of different-sized samples
Faster Speed
Hundreds to thousands of times faster than confocal microscopy and two-photon fluorescence microscopy
Multi-Color
405nm, 488nm, 550nm, 647nm, etc. can be used for imaging
Unparalleled Resolution
Ultra-high resolutions to visualize the brain's microstructure and cellular organization with exceptional clarity.
High Signal Intensity
Ability to preserve strong fluorescence signals for multiple fluorescent proteins.
Applications
The versatility and precision of Creative Biolabs' Brain Imaging Platform make it applicable to a wide range of research areas in neuroscience. Some notable applications include:
Brain Tissue Imaging
Mouse brains, tree shrew brains, marmoset brains, macaque brains.
AI Pathological Analysis
High-precision and fast fluorescence imaging analysis of internal structures in pathological slices related to neurological disorders.
Neural Circuit Analysis
Fast analysis of tracing virus for rapid analysis of behavior-related neural circuits.
Neural Gene Profiling
Suitable for analyzing the expression of immediate-early genes in brain tissue.
With its high-resolution imaging capabilities, advanced data analysis algorithms, and integration with clinical studies, our platform provides researchers with a powerful tool to unravel the complexities of the human brain. For further information or to initiate a discussion regarding your unique requirements, please contact us today to explore the possibilities of collaborating with our company.
Reference
- Zhu, Jingtan, et al. "MACS: rapid aqueous clearing system for 3D mapping of intact organs." Adv Sci (Weinh). 2020;7(8):1903185. Distributed under Open Access License CC BY 4.0 without modification.
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