Creative Biolabs

Olfactory System

Olfactory System

Fig.1 Olfactory System

The sensations of body perception are divided into two categories: general sensations such as touch, pressure, pain and temperature, as well as special sensations such as vision, hearing, taste, smell, and body position and movement. The olfactory system or smell is the sensory system used for smell (olfaction). The sense of smell is a special sensation directly related to a specific organ. Most mammals and reptiles have a primary olfactory system and an auxiliary olfactory system. The main olfactory system detects substances in the air, while the auxiliary system detects stimuli in the liquid phase. Olfactory and taste (taste system) are often called chemosensory systems together because they both provide the brain with information about the chemical composition of objects through a process called transduction.

Odor information originates from the epithelium of the nasal cavity and is transmitted to the brain through the olfactory nerve (cranial nerve 1-CNI) and components of the olfactory pathway. The decreased sense of smell is related to Parkinson's disease, so it can be an important clinical sign of this or other diseases or injuries.

In order to better understand the olfactory nerve and its clinical significance, as well as the connection between olfactory signal pathways and brain regions related to memory (and behavior), Creative Biolabs provides a complete list of neurological research tools to support customer’s research.

Clinical Significance

Damage to the olfactory system may be caused by head trauma, cancer, infection, inhalation of toxic fumes, or neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease). These conditions can cause insomnia. On the contrary, recent findings indicate that the molecular aspects of olfactory dysfunction can be regarded as a marker of amyloidogenesis-related diseases, and may even be causal by disrupting the transport and storage of multivalent metal ions.

Olfaction problems can be divided into different types according to their malfunction. Olfactory dysfunction may be complete (insomnia), incomplete (partial insomnia, hypotonic or micro-insomnia), deformed (insomnia), or characterized by spontaneous sensations, such as hallucinations. Hyperosmolarity is a rare disease characterized by an abnormally enhanced sense of smell. Like vision and hearing, olfactory problems can be bilateral or unilateral. If it is on both sides of the nose, it is called bilateral anorexia or general anorexia.

Creative Biolabs provides a complete list of antibodies and protein products to help our customers better understand the interaction between the olfactory system and the neurological diseases. With our easy-to-use guide below, choose the best marker tools you need for your research.


For Research Use Only. Not For Clinical Use.
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