Lumbar Disk Disease Related Research Tools
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Lumbar disk disease (Herniated Disk), a major cause of lower back pain, is the drying out of the spongy interior matrix of an intervertebral disc in the spine. It is also known as lumbar spondylosis. Pain, loss of muscle strength and loss of touch sensation may occur in patients with lumbar disk disease. In severe cases, a herniated disc can produce a dysfunction of the nerve.
Lumbar disk disease is caused by a change in the structure of the normal disk. Most of the time, lumbar disk disease results from aging. However, an inheritable gene variation may cause increased susceptibility. Cartilage intermediate-layer protein (CILP) is a normal component of the disk tissue. The CILP variant is hypothesized to disrupt the normal building and maintenance of the cartilage. People with CILP mutant are 1.6 times more likely to develop the disease.
Creative Biolabs has a comprehensive list of bio-reagents involving in lumbar disk disease (herniated disk) research. The following is a part of our featured products that may be associated with your areas of interest.
- Neural Cell Lines
- Basal Media
- Media Supplements
- Specialty Media
- Cell Differentiation Media
- Cell Dyes
- Neural Cell Culture Antibiotics
- Assay Kits
- Buffers & Solutions
- Neural Antibodies
- Recombinant Proteins
- Cytokines
- Growth Factors
- Small Molecules
- Toxins
- Agonists
- Antagonists
- Animal Models
- Tools & Devices
Creative Biolabs appreciates the critical roles that our products play in research efforts to further Lumbar disk disease (Herniated disk) diagnosis and treatment.
Pathways Related to Creative Biolabs Products of Lumbar Disk Disease (Herniated Disk)
| Super pathways | Genes |
| ERK signaling | IL6, IL1B, IL1A, COL9A3, COL9A2, COL11A2 |
| Phospholipase-C pathway | IL6, COL9A3, COL9A2, COL11A2, COL11A1 |
| Focal adhesion | THBS2, COL9A3, COL9A2, COL11A2, COL11A1 |
| Collagen chain trimerization | MMP9, COL9A3, COL9A2, COL11A2, COL11A1 |
| Degradation of the extracellular matrix | MMP9, COL9A3, COL9A2, COL11A2, COL11A1, ASPN |
| T cell receptor signaling pathway | IL6, IL1B, IL1A, IFNG |
| IL-17 family signaling pathway | MMP9, IL6, IL1B, IFNG |
| Toll comparative pathway | IL6, IL1B, IL1A, IFNG |
For Research Use Only. Not For Clinical Use.
Target
Related Products
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NeuroMab™ Rabbit Anti-CTSD Monoclonal Antibody (CBP7242) [CAT#: NAB-0720-Z9754]
Cathepsin D Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB; FCM; ICC; IF; IHC-P
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3523
NeuroMab™ Mouse Anti-PCYT1A Monoclonal Antibody (CBP6978) [CAT#: NAB-0720-Z8500]
CT A Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ICC; IF; IHC-P; Protein Array
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3354
NeuroMab™ Mouse Anti-Mouse Kcnmb2 Monoclonal Antibody (CBP6886) [CAT#: NAB2109P232]
Anti-BK channel BETA2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse
- Applications:
- WB; IHC; IP
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3329
NeuroMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP6480) [CAT#: NAB-1021-R0349]
Mouse monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC; ICC; IF
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3304
NeuroMab™ Mouse Anti-PRKAR2A Monoclonal Antibody (CBP6247) [CAT#: NAB-1021-R0102]
Mouse monoclonal to PRKAR2A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3279
NeuroMab™ Mouse Anti-P-tau181 Monoclonal Antibody (CBP6091) [CAT#: NAB-0421-R0773]
Mouse monoclonal to P-tau181
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3254
NeuroMab™ Mouse Anti-SETD2 Monoclonal Antibody (CBP6052) [CAT#: NAB-0421-R0626]
Mouse monoclonal to SETD2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3229
NeuroMab™ Mouse Anti-FABP4 Monoclonal Antibody (CBP6006) [CAT#: NAB-0421-R0411]
Mouse monoclonal to FABP4
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- ELISA; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3204
NeuroMab™ Mouse Anti-FABP3 Monoclonal Antibody (CBP5969) [CAT#: NAB-0421-R0354]
Mouse monoclonal to FABP3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3179
NeuroMab™ Mouse Anti-NEFL Monoclonal Antibody (CBP5938) [CAT#: NAB-0421-R0295]
Mouse monoclonal to NEFL
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3154
NeuroMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5899) [CAT#: NAB-0421-R0156]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3129
NeuroMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5873) [CAT#: NAB-0421-R0127]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3104
NeuroMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5846) [CAT#: NAB-0421-R0039]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3079
NeuroMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5821) [CAT#: NAB-0421-R0012]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3054
NeuroMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP5310) [CAT#: NAB-0321-R0760]
Mouse Monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IF; IHC; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2947
NeuroMab™ Mouse Anti-Amyloid Beta Monoclonal Antibody (CBP5259) [CAT#: NAB-0321-R0555]
Mouse Monoclonal to Amyloid Beta
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IF; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2922
NeuroMab™ Mouse Anti-Zimp Monoclonal Antibody (CBP5221) [CAT#: NAB-2103-P1131]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2897
NeuroMab™ Mouse Anti-Vangl Monoclonal Antibody (CBP5195) [CAT#: NAB-2103-P1082]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2872
NeuroMab™ Mouse Anti-Testican Monoclonal Antibody (CBP5162) [CAT#: NAB-2103-P1014]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2847
NeuroMab™ Mouse Anti-Sarcoplasmic Reticulum Monoclonal Antibody (CBP5120) [CAT#: NAB-2103-P943]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2822
NeuroMab™ Mouse Anti-Shank Monoclonal Antibody (CBP5087) [CAT#: NAB-2103-P894]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2797
NeuroMab™ Mouse Anti-Prickle Monoclonal Antibody (CBP5048) [CAT#: NAB-2103-P818]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2772
NeuroMab™ Mouse Anti-PACSIN Monoclonal Antibody (CBP5009) [CAT#: NAB-2103-P751]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat
- Applications:
- WB; IP; IF
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2747
NeuroMab™ Mouse Anti-NP Monoclonal Antibody (CBP4979) [CAT#: NAB-2103-P703]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2722
NeuroMab™ Mouse Anti-NGFR Monoclonal Antibody (CBP4942) [CAT#: NAB-2103-P656]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2697
NeuroMab™ Mouse Anti-neurolysin Monoclonal Antibody (CBP4911) [CAT#: NAB-2103-P598]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2672
NeuroMab™ Mouse Anti-netrin-1 Monoclonal Antibody (CBP4882) [CAT#: NAB-2103-P546]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2647
NeuroMab™ Mouse Anti-Myelin Monoclonal Antibody (CBP4850) [CAT#: NAB-2103-P499]
- Host Species:
- Mouse
- Species Reactivity:
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- Applications:
- WB; IF; IHC-P
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2622
NeuroMab™ Mouse Anti-MA Monoclonal Antibody (CBP4817) [CAT#: NAB-2103-P447]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2597
NeuroMab™ Mouse Anti-Homer Monoclonal Antibody (CBP4788) [CAT#: NAB-2103-P385]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2572
Product
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Cells
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
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Kits
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
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- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
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Tracers
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
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- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- AAV2/9-hSyn-Flpo-EGFP-WPRE-pA (Cat#: NTA-2012-ZP149)
- PRV-CAG-EGFP (Cat#: NTA-2011-ZP14)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
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Gene Related Products
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Biospecimens
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Cell Assay Reagents
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