Cerebral Aneurysm Related Research Tools
The cerebral aneurysm is an abnormal bulge or ballooning of an artery in the brain that can put pressure on the surrounding nerves and brain tissues. It is also known as an intracranial aneurysm or brain aneurysm. There are three types of cerebral aneurysms: saccular aneurysms, fusiform aneurysms and dissecting aneurysms. Saccular aneurysms are the most common type, accounting for 90% of cerebral aneurysm cases.
A cerebral aneurysm accompanies robust structural changes in the vascular wall. Hemodynamic stress, inflammatory responses, extracellular matrix defects and degeneration have been suggested as the key components leading to the structural fragility in the arterial wall. However, the exact pathogenesis of cerebral aneurysm formation, growth, and rupture remains to be discovered.
Fig.1 Structural alteration of a cerebral aneurysm.
Creative Biolabs provides cerebral aneurysms related reagents, such as recombinant proteins, antibodies, cell lines and analytical kits. These high-quality products can be used in genetic, imaging, and laboratory tests and help to study the natural course and pathophysiology of cerebral aneurysms.
We are here to offer an opportunity to better identify aneurysms that have a high risk of rupture.
Pathophysiological Factors Involved in Aneurysm Formation
| Molecular and histological changes | |
| Endothelial cell |
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| Smooth muscle cell |
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| Inflammation |
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| Extracellular matrix |
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| Internal elastic lamina |
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For Research Use Only. Not For Clinical Use.
Target
Premade Viruses
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iNeuMab™ Rat Anti-LGALS3 Monoclonal Antibody (CBP7324) [CAT#: NAB-0720-Z10030]
Galectin 3 Rat Monoclonal Antibody
- Host Species:
- Rat
- Species Reactivity:
- Mouse; Human
- Applications:
- FCM
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-LAMA4 Monoclonal Antibody (CBP7282) [CAT#: NAB-0720-Z9909]
Laminin alpha 4/LAMA4 Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; WB; IP
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-CTSD Monoclonal Antibody (CBP7230) [CAT#: NAB-0720-Z9697]
Cathepsin D Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- Protein Array; WB; IHC-P
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Human VIM Monoclonal Antibody (CBP6964) [CAT#: NAB2109P326]
Anti-Vimentin Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; IF; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Human LAMP1 Monoclonal Antibody (CBP6872) [CAT#: NAB2109P173]
Anti-LAMP1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; IF; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-NEFM Monoclonal Antibody (CBP6463) [CAT#: NAB-1021-R0330]
Mouse monoclonal to NEFM
- Host Species:
- Mouse
- Species Reactivity:
- Xenopus; Hamster; Human; Monkey
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-CGRP Monoclonal Antibody (CBP6206) [CAT#: NAB-1021-R0061]
Mouse monoclonal to CGRP
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Aβ42 Monoclonal Antibody (CBP6075) [CAT#: NAB-0421-R0752]
Mouse monoclonal to Aβ42
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ELISA; Dot
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-HTT Monoclonal Antibody (CBP6046) [CAT#: NAB-0421-R0604]
Mouse monoclonal to HTT
- Host Species:
- Mouse
- Species Reactivity:
- Human; Monkey; Mouse; Rat; Dog
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-FABP3 Monoclonal Antibody (CBP5996) [CAT#: NAB-0421-R0401]
Mouse monoclonal to FABP3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-FABP1 Monoclonal Antibody (CBP5965) [CAT#: NAB-0421-R0349]
Mouse monoclonal to FABP1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ELISA; FC; IF; IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-S100B Monoclonal Antibody (CBP5933) [CAT#: NAB-0421-R0280]
Mouse monoclonal to S100B
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5895) [CAT#: NAB-0421-R0152]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5869) [CAT#: NAB-0421-R0120]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human; Monkey; Mouse; Rat
- Applications:
- IF; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5842) [CAT#: NAB-0421-R0033]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5817) [CAT#: NAB-0421-R0008]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-NEFM Monoclonal Antibody (CBP5302) [CAT#: NAB-0321-R0723]
Mouse Monoclonal to NEFM
- Host Species:
- Mouse
- Species Reactivity:
- Guinea Porcine; Hamster; Human; Monkey; Rabbit; Xenopus
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Amyloid Beta Monoclonal Antibody (CBP5254) [CAT#: NAB-0321-R0550]
Mouse Monoclonal to Amyloid Beta
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- FC; IF; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
iNeuMab™ Mouse Anti-X11 Monoclonal Antibody (CBP5217) [CAT#: NAB-2103-P1110]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF
iNeuMab™ Mouse Anti-Unc Monoclonal Antibody (CBP5190) [CAT#: NAB-2103-P1062]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-Tachykinin Monoclonal Antibody (CBP5158) [CAT#: NAB-2103-P1010]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-Sarcoplasmic Reticulum Monoclonal Antibody (CBP5116) [CAT#: NAB-2103-P939]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-SAP 97 Monoclonal Antibody (CBP5081) [CAT#: NAB-2103-P887]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human; Canine
- Applications:
- WB; IP; IF; IHC-P
iNeuMab™ Mouse Anti-Post-Synaptic Density Protein Monoclonal Antibody (CBP5038) [CAT#: NAB-2103-P802]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-p55 Monoclonal Antibody (CBP5004) [CAT#: NAB-2103-P746]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Nogo Monoclonal Antibody (CBP4973) [CAT#: NAB-2103-P696]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-NF Monoclonal Antibody (CBP4937) [CAT#: NAB-2103-P627]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human; Xenopus; Bovine
- Applications:
- WB; IP; IF; IHC-P
iNeuMab™ Mouse Anti-neuroligin Monoclonal Antibody (CBP4907) [CAT#: NAB-2103-P589]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-NETO Monoclonal Antibody (CBP4877) [CAT#: NAB-2103-P540]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; ELISA
iNeuMab™ Mouse Anti-Munc Monoclonal Antibody (CBP4846) [CAT#: NAB-2103-P490]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
Product
Hot Products
Antibodies
- NeuroMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody(NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
- iNeuMab™ Anti-F-Spondin/SPON1 Antibody, Clone 3F4 (Cat#: NRZP-0822-ZP4740)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P517) (Cat#: NRP-0422-P517)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- NeuroMab™ Anti-GARP Antibody(NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2293) (Cat#: NRP-0422-P2293)
- Mouse Anti-SCN5A Monoclonal Antibody (CBP708) (Cat#: NAB-0720-Z2720)
- NeuroMab™ Anti-TREM2 BBB Shuttle Antibody(NRZP-1022-ZP4114) (Cat#: NRZP-1022-ZP4114)
- iNeuMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- iNeuMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
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Cells
- iNeu™ Human Oligodendrocyte Progenitor Cells (OPCs) (Cat#: NCL-2103-P49)
- Human Retinal Epithelial Cell ARPE-19 (Cat#: NCL2110P069)
- Mouse Microglia N9 (Cat#: NCL2110P073)
- Green Fluorescent Tau SH-SY5Y cell Line (Cat#: NCL2110P219)
- iNeu™ Human Sensory Neurons (Cat#: NCL-2103-P62)
- Rat Schwann Cells RSC96, Immortalized (Cat#: NCL-2108P21)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- Human Astrocytes, Immortalized (Cat#: NCL-2105-P182-AM)
- Green Fluorescent Alpha-synuclein SH-SY5Y Cell Line (Cat#: NCL2110P209)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
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Kits
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
More
Tracers
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA (Cat#: NTA-2010-TT342)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- Dextran, NHS Activated, 40 kDa (Cat#: NRZP-0722-ZP124)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
More
Gene Related Products
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
More
Biospecimens
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
More
Cell Assay Reagents
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
More
