Neural Progenitor Cell Products

Neural progenitor cells (NPCs) are undifferentiated multipotent or pluripotent cells that have the ability to self-renew and differentiate into various cell types. They maintain self-renewal and differentiate into different types of neurons during the development of the nervous system. The balance between differentiation and self-renewal depends on the synergistic action of multiple growth factors. Neural progenitor cells are derived from multipotent cells, are capable of self-renewal, and have the ability to divide.

At Creative Biolabs, our neural progenitor cell products demonstrate excellent proliferation, differentiation, and functional properties in vitro and in vivo. We offer a comprehensive range of neural stem cell products, including human primary NPCs and human induced pluripotent stem cell (hiPSC)-derived NPCs. To learn more about our products or submit a project inquiry, please contact us today.

Product Overview

	Primary Neural Progenitor Cells Human Neuronal Progenitor Stem Cells Rat Neuronal Progenitor Cells
	Human iPSC-derived Neural Progenitor Cells iNeu™ Human Neural Progenitor Cells - Normal Donor 1 iNeu™ Human Neural Progenitor Cells - Parkinson's Disease iNeu™ Human Neural Precursor Cells - Alzheimer's Disease iNeu™ Human Neural Precursor Cells - Epilepsy
	Immortalized Neural Progenitor Cells Mouse Neural Progenitor Cells, Immortalized

Features & Benefits

• Our neural progenitor cells undergo a rigorous screening and culture process to ensure purity and viability. They are capable of self-renewal and differentiation into a variety of neuronal and glial cell types, including astrocytes, oligodendrocytes, and neurons.
• Our neural progenitor cell culture media is designed to support the efficient expansion of neural progenitor cells, enabling them to be expanded 3-5 times per generation and cultured for at least 10 generations. This process maintains pluripotency and minimizes spontaneous neuronal differentiation.
• Additionally, we offer optimized directed differentiation media to facilitate the differentiation into specific neural cell types. These media typically contain a combination of growth factors and cytokines, which facilitate efficient differentiation and functional maintenance of cells.

Applications

• NPCs have demonstrated efficacy in the treatment of a range of neurological disorders, including AD, PD, multiple sclerosis, spinal cord injury, and stroke. For instance, in the treatment of AD, NPC transplantation therapy has garnered significant interest due to its capacity to enhance synaptic connectivity and functional recovery.
• NPCs play a vital role in nerve injury models by secreting neuroprotective factors such as VEGF, EGF, and FGF-2, which promote neuronal survival and axonal growth.

For further details or to place an order, please contact us. Our technical support team is available to address any inquiries you may have regarding our products or custom services.

References

1. Ma, Yizhao, et al. "Exosomes released from neural progenitor cells and induced neural progenitor cells regulate neurogenesis through miR-21a." Cell Communication and Signaling 17 (2019): 1-10.
2. Kang, Sai, et al. "Characteristic analyses of a neural differentiation model from iPSC-derived neuron according to morphology, physiology, and global gene expression pattern." Scientific reports 7.1 (2017): 12233.
3. Song, Yuyu, et al. "A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line." Scientific Data 6.1 (2019): 1-17.
4. Distributed under Open Access license CC BY 4.0, without modification.