Guillain-Barré Syndrome Related Research Tools
Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis, is a rare condition in which a person’s immune system attacks the peripheral nerves. The symptoms of Guillain–Barré syndrome are numbness, tingling, pain and weakness of the legs and arms.
Guillain-Barré syndrome is due to the nerve dysfunction by an immune attack on the nerve cells of the peripheral nervous system. Different types of Guillain-Barré syndrome are categorized by different types of immune attack. For instance, the demyelinating variant is characterized by the damage to the myelin sheath from white blood cells preceded by the activation of a group of blood proteins. The axonal variant is mediated by the IgG antibodies and the complement components against the cell membrane covering the axons.
Fig.1 Immune system attacks nerves in the body with Guillain-Barre syndrome.
Creative Biolabs offers a series of research tools needed to study the mechanisms of Guillain-Barré syndrome. Some tools, such as autoimmune neuritis animal models, kinase enzymes and complement inhibitors, proteins and antibodies, have been verified in laboratory tests.
Pathways related to Guillain-Barre Syndrome
| Super pathways | Genes |
| Measles | TNF, HLA-DRB1, HLA-DQB1, HLA-DQA1, FAS |
| Herpes simplex virus 1 infection | TNF, HLA-DRB1, HLA-DQB1, HLA-DQA1, FAS |
| Allograft rejection | TNF, HLA-DRB1, HLA-DQB1, HLA-DQA1, FAS, CD40LG |
| NF-kappa B signaling | TNFRSF1B, TNF, FAS, CD79A, CD40LG |
| ICos-ICosL pathway in T-helper cell | HLA-DRB1, HLA-DQB1, HLA-DQA1, CD40LG |
Cellular components related to Guillain-Barre Syndrome
| Cellular components | Genes |
| External side of plasma membrane | TNF, MOG, HLA-DRB1, CD79A, CD40LG |
| Membrane raft | TNFRSF1B, TNF, FAS, CD79A |
| Endocytic vesicle membrane | HLA-DRB1, HLA-DQB1, HLA-DQA1 |
| Myelin sheath | PMP2, MPZ, MBP |
For Research Use Only. Not For Clinical Use.
Target
Premade Viruses
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iNeuMab™ Rabbit Anti-AFDN Monoclonal Antibody (CBP7284) [CAT#: NAB-0720-Z9912]
Afadin Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IHC-P; IHC-Fr
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-GPHN Monoclonal Antibody (CBP7235) [CAT#: NAB-0720-Z9707]
Gephyrin Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- ICC; IF; FCM; IHC-P; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Human VAMP Monoclonal Antibody (CBP6968) [CAT#: NAB2109P330]
Anti-Synaptobrevin Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Human GFAP Monoclonal Antibody (CBP6877) [CAT#: NAB2109P207]
Anti-GFAP R416WT Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP6475) [CAT#: NAB-1021-R0344]
Mouse monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC; ICC; IP
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-MAFG Monoclonal Antibody (CBP6225) [CAT#: NAB-1021-R0080]
Mouse monoclonal to MAFG
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Aβ40 Monoclonal Antibody (CBP6089) [CAT#: NAB-0421-R0766]
Mouse monoclonal to Aβ40
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-HTT Monoclonal Antibody (CBP6050) [CAT#: NAB-0421-R0611]
Mouse monoclonal to HTT
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; IF
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-FABP3 Monoclonal Antibody (CBP6000) [CAT#: NAB-0421-R0405]
Mouse monoclonal to FABP3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-FABP4 Monoclonal Antibody (CBP5967) [CAT#: NAB-0421-R0351]
Rabbit monoclonal to FABP4
- Host Species:
- Rabbit
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-S100B Monoclonal Antibody (CBP5936) [CAT#: NAB-0421-R0288]
Mouse monoclonal to S100B
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ELISA; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5897) [CAT#: NAB-0421-R0154]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5871) [CAT#: NAB-0421-R0122]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IF; IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5844) [CAT#: NAB-0421-R0037]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5819) [CAT#: NAB-0421-R0010]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Bax Monoclonal Antibody (CBP5307) [CAT#: NAB-0321-R0746]
Mouse Monoclonal to Bax
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Amyloid Beta Monoclonal Antibody (CBP5256) [CAT#: NAB-0321-R0552]
Mouse Monoclonal to Amyloid Beta
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- FC; IF; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
iNeuMab™ Mouse Anti-X11 Monoclonal Antibody (CBP5219) [CAT#: NAB-2103-P1112]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-UNC45 Monoclonal Antibody (CBP5193) [CAT#: NAB-2103-P1072]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Testican Monoclonal Antibody (CBP5160) [CAT#: NAB-2103-P1012]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Sarcoplasmic Reticulum Monoclonal Antibody (CBP5118) [CAT#: NAB-2103-P941]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-Serine Racemase Monoclonal Antibody (CBP5084) [CAT#: NAB-2103-P891]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-Presenilin Monoclonal Antibody (CBP5046) [CAT#: NAB-2103-P813]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-PACRG Monoclonal Antibody (CBP5007) [CAT#: NAB-2103-P749]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-NP Monoclonal Antibody (CBP4976) [CAT#: NAB-2103-P700]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-NF Monoclonal Antibody (CBP4939) [CAT#: NAB-2103-P629]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human; Xenopus; Bovine
- Applications:
- WB; IP; IF
iNeuMab™ Mouse Anti-neurolysin Monoclonal Antibody (CBP4909) [CAT#: NAB-2103-P596]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Netrin G1 Monoclonal Antibody (CBP4879) [CAT#: NAB-2103-P543]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Myelin Monoclonal Antibody (CBP4848) [CAT#: NAB-2103-P497]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-LNX Monoclonal Antibody (CBP4814) [CAT#: NAB-2103-P442]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
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