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Creative Biolabs

Guillain-Barré Syndrome Related Research Tools

Guillain-Barré syndrome (GBS), the most common cause of acute flaccid paralysis, is a rare condition in which a person’s immune system attacks the peripheral nerves. The symptoms of Guillain–Barré syndrome are numbness, tingling, pain and weakness of the legs and arms.

Guillain-Barré syndrome is due to the nerve dysfunction by an immune attack on the nerve cells of the peripheral nervous system. Different types of Guillain-Barré syndrome are categorized by different types of immune attack. For instance, the demyelinating variant is characterized by the damage to the myelin sheath from white blood cells preceded by the activation of a group of blood proteins. The axonal variant is mediated by the IgG antibodies and the complement components against the cell membrane covering the axons.

 Immune system attacks nerves in the body with Guillain-Barre syndrome. Fig.1 Immune system attacks nerves in the body with Guillain-Barre syndrome.

Creative Biolabs offers a series of research tools needed to study the mechanisms of Guillain-Barré syndrome. Some tools, such as autoimmune neuritis animal models, kinase enzymes and complement inhibitors, proteins and antibodies, have been verified in laboratory tests.

Pathways related to Guillain-Barre Syndrome

Super pathways Genes
Measles TNF, HLA-DRB1, HLA-DQB1, HLA-DQA1, FAS
Herpes simplex virus 1 infection TNF, HLA-DRB1, HLA-DQB1, HLA-DQA1, FAS
Allograft rejection TNF, HLA-DRB1, HLA-DQB1, HLA-DQA1, FAS, CD40LG
NF-kappa B signaling TNFRSF1B, TNF, FAS, CD79A, CD40LG
ICos-ICosL pathway in T-helper cell HLA-DRB1, HLA-DQB1, HLA-DQA1, CD40LG

Cellular components related to Guillain-Barre Syndrome

Cellular components Genes
External side of plasma membrane TNF, MOG, HLA-DRB1, CD79A, CD40LG
Membrane raft TNFRSF1B, TNF, FAS, CD79A
Endocytic vesicle membrane HLA-DRB1, HLA-DQB1, HLA-DQA1
Myelin sheath PMP2, MPZ, MBP
For Research Use Only. Not For Clinical Use.

Target

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Afadin Rabbit Monoclonal Antibody

Host Species:
Rabbit
Species Reactivity:
Mouse; Rat; Human
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WB; IHC-P; IHC-Fr
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3546

Gephyrin Rabbit Monoclonal Antibody

Host Species:
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ICC; IF; FCM; IHC-P; WB
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3521

Anti-Synaptobrevin Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
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WB; IHC
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Anti-GFAP R416WT Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
ELISA; WB
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3327

Mouse monoclonal to IL1A

Host Species:
Mouse
Species Reactivity:
Human
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WB; IHC; ICC; IP
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Mouse monoclonal to MAFG

Host Species:
Mouse
Species Reactivity:
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Host Species:
Mouse
Species Reactivity:
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Mouse monoclonal to HTT

Host Species:
Mouse
Species Reactivity:
Human; Mouse
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WB; IF
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3227

Mouse monoclonal to FABP3

Host Species:
Mouse
Species Reactivity:
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Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3202

Rabbit monoclonal to FABP4

Host Species:
Rabbit
Species Reactivity:
Human; Mouse; Rat
Applications:
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3177

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Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3152

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Host Species:
Mouse
Species Reactivity:
Human
Applications:
ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3127

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Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3102

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Host Species:
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Species Reactivity:
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3077

Mouse monoclonal to UCHL1

Host Species:
Mouse
Species Reactivity:
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Applications:
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Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3052

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Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IHC; WB
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2945

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Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
FC; IF; WB
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2920
Host Species:
Mouse
Species Reactivity:
Mouse
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WB; IP; IF; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2895
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
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WB; IP; IF; ELISA
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Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2870
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
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WB; IP; IF; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2845
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
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WB; IP; IF; IHC-P; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2820
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
WB; IP; IF; IHC-P; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2795
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
WB; IP; IF; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2770
Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; IP; IF; IHC-P; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2745
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
WB; IP; IF; IHC-P; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2720
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human; Xenopus; Bovine
Applications:
WB; IP; IF
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2695
Host Species:
Mouse
Species Reactivity:
Human
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WB; IP; IF; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2670
Host Species:
Mouse
Species Reactivity:
Human
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WB; IP; IF; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2645
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
WB; IP; IF; IHC-P; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2620
Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
WB; IP; IF; ELISA
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2595
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