Cell-based Assay
Creative Biolabs offers a cutting-edge suite of advanced cell assays that revolutionize the landscape of neuroscience research.
Examples of Cells-based Assays We Deliver
Creative Biolabs offers a diverse range of cell types, ranging from primary neuronal cultures to cell lines derived from neural tissue. These resources are employed to enhance the investigation of cellular processes under controlled conditions, ultimately leading to a deeper comprehension of the nervous system's structure and operation. Our collection of cellular assays comprises a variety of techniques, each meticulously designed to elucidate distinct aspects of cellular activity.
Here, we present a selection of frequently employed cell types within our cell-based service:
- Oligodendrocyte Precursor Cell (OPC) Assay
- Neuron Assay
- Cortical Neurons
- Sensory Neurons
- Motor Neurons
- Hippocampal Neurons
- Central/Peripheral Neurons
- iPSC-derived Neurons
- Microglia Assay
- Astrocyte Assay
- Schwann Cell Assay
- Neurons, Astrocytes and Microglia Co-culture Assay
- Retinal Cells Assay
- Neural Stem Cells Assay
- Human iPSC-derived Cell (from neurological disease patient donor) Assay
Depending on the specific research goals, we can also provide customized cell model-based assays. This helps researchers identify potential neurotoxic compounds, evaluate the safety of pharmaceutical agents, and gain insights into cell death pathways relevant to neurodegenerative diseases.
Examples of Measurements We Can Perform
Assays | Introduction | Measurements |
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Cell Viability and Cytotoxicity Assays | Use MTT/CCK8 assay, CellTiter-Glo assay, LDH, Annexin V-FITC, and resazurin-based assays to determine the viability. |
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Neurite Outgrowth Assays | Evaluate the ability of neurons to extend and develop neurites (axons and dendrites). |
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Neural Differentiation Assays | Evaluate differentiation of inducing stem cells or progenitor cells to neurons or glial cells. |
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3D Neural Culture Assays | Use 3D spheroids or organoids to mimic the complex in vivo microenvironment of neural tissues. | Brain/retinal spheroids or organoids assay |
Calcium Imaging Assays | Fluorescent calcium indicators are used to visualize changes in calcium concentration in response to various stimuli or drugs. | Calcium level |
Neurotransmitter Release Assays | Study synaptic function, dysfunction, and plasticity | Neurotransmitters level |
General Process
Designing Customized Assays
At Creative Biolabs, we understand that every neuroscience inquiry is unique. Our dedicated team collaborates closely with researchers to design customized neural cell assays tailored to their specific questions. This ensures that the assays precisely target the neural cell types and functional aspects of interest, maximizing the quality and relevance of the data obtained.
Please feel free to contact us and discover how we take your neuroscience research to new heights.