Neural Stem Cell Markers
Neural stem cells (NSC) are present in the developing nervous system of mammals and adults. They are pluripotent cells in the nervous system, capable of self-renewal and unlimited proliferation without generating differentiated progenitor cells. Progenitor cells eventually differentiate into the basic lineage of the nervous system, including oligodendrocytes, astrocytes, neurons and glial cells. In recent years, the use of neural stem cells in research and medicine has become increasingly common. Several studies have revealed the important clinical application of neural stem cells in the treatment of central nervous system diseases including Parkinson's disease, Alzheimer's disease and spinal cord repair.
Creative Biolabs provides a series of products that can be used to detect the expression of neural stem cell markers. Commonly used markers for neural stem cells include Nestin and SOX2. The transcription factor SOX2 is known to be expressed at high levels in the developing CNS neuroepithelium, and is considered to be essential for the proliferation and differentiation of neural stem cells. In addition to intracellular molecules, products can also be used to study proteins expressed on the cell surface, including ABCG2, FGF R4 and Frizzled-9.
With our easy-to-use guide below, choose the best cell marker tools you need for your research.