Pain Drug Discovery Service

Creative Biolabs is a prestigious biotechnology company with extensive experience in neuroscience, especially pain research. We have established a complete experimental platform and a professional team, with our advanced platform and extensive expertise, we focus on providing customized one-stop pain-related services such as animal model establishment, targeted drug screening, and drug development for our customers all over the world.

Introduction to Pain

Pain is a signal that something may be abnormal in the nervous system. There are two types of pain: acute and chronic. Acute pain usually comes on suddenly due to inflammation, injury, or disease. It can usually be diagnosed and treated. Chronic pain lasts a long time and causes serious problems. Pain can cause unpleasant symptoms such as nausea, dizziness, weakness, or drowsiness. Additionally, it also adversely affects moods such as anger, depression, mood swings, or irritability. Perhaps most importantly, pain changes the way you live and affects your work, relationships, and independence. Pain is not always curable, but there are many ways to treat it. Medication plays a vital role in pain, especially pain relievers. Acetaminophen, for example, may help relieve all types of pain, especially mild to moderate pain. Other medications, such as antidepressants and topical pain relievers, can also relieve pain. Developing new pain medications has always been a focus of drug development.

Fig.1 Types of pain and chronicity. (Zolezzi, 2022)

What Can We Do?

At Creative Biolabs, our professional team provides a full range of preclinical drug discovery services, providing professional support at every stage from disease target specification to candidate drug selection. Our dedicated experts will provide you with tailored scientific solutions that add significant value to your drug discovery project. Diverse pain models and different in vivo and in vitro assays underpin our high-quality service.

Fig.2 Pain drug discovery services. (Creative Biolabs)

Various Pain Models

Currently, Creative Biolabs provides various pain models to accelerate preclinical drug screening, which are listed below:

❉ Cancer pain models

❉ Wound healing models

❉ Post-operative pain models

❉ Inflammatory pain models

❉ Neuropathic pain models

Cell Models

• Primary Neuronal Cell Culture Models
• Human iPSC Derived Neuronal Cell Culture Models
• Organotypic Brain Slice Models

Feature Assays

Preclinical drug screening is a complicated process. At Creative Biolabs, our experienced scientists will work with you to design your experiments. Creative Biolabs has developed many suitable preclinical pain models to assist with your pain drug discovery and development program. Furthermore, a variety of in vivo and in vitro assays are available. Please contact us to discuss your project for professional assistance and customized solutions.

Reference

1. Zolezzi, D. M.; et al. Chronic neuropathic pain is more than a perception: systems and methods for an integral characterization. Neuroscience & Biobehavioral Reviews. 2022, 104599.