Calcium Channel Related Research Reagents
Calcium channels are ion channels that have selective permeability to calcium ions. Calcium is a vital signaling molecule that can mediate muscle contraction, nerve transmission, and gene expression. Disruption of normal calcium channel function causes a variety of diseases, such as inherited calcium channel diseases including neurological diseases (X-linked night blindness) and hemiplegic migraine; musculoskeletal diseases such as hypokalemic periodic paralysis and malignant hyperthermia; and cardiovascular diseases, including ventricular cardiomyopathy and familial polymorphic ventricular tachycardia.
There are two main types of calcium channels: voltage-gated calcium channels and ligand-gated calcium channels.
Voltage-gated calcium channels
Voltage-gated calcium channels (VGCC), also known as voltage-dependent calcium channels (VDCC), are a set of voltage-gated channels found in the cell membrane that can excite cells (e.g., muscles, glial cells, neurons, etc.). The ion channel is permeable to calcium ion Ca2+.
Ligand-gated calcium channels
Ligand-gated calcium channels: the receptor-operated calcium channels, are activated by ligand binding. For example, IP3 receptor releases calcium ions from ER / SR in response to IP3.
Creative Biolabs provides a variety of calcium channel blockers, which can prevent calcium ions from passing through the channels on the cell membrane, and are used to treat hypertension and epilepsy. Our product profolio also lncludes a series of products for calcium channel receptors research, including monoclonal antibodies, labeled antibodies, proteins, assay kits, and small molecule activiators and inhibitors.
Please browse the options below to take a deeper look at the tools for your research needs.
Target
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Calcium binding protein
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC
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Calcium binding protein
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC; WB
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Calcium binding protein
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC; WB
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Anti-CACNA1C Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; ICC; WB; IP
- Conjugation:
- Unconjugated
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Anti-CACNB2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ICC; IF; IHC; WB
- Conjugation:
- Unconjugated
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Anti-CACNA1H Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; ICC; WB
- Conjugation:
- Unconjugated
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Anti-CACNA1D Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ICC; FC; IF; IP; IHC; WB
- Conjugation:
- Unconjugated
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Anti-CACNA1D Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- ICC; IF; WB
- Conjugation:
- Unconjugated
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Anti-CACNA1G Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated
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- Applications:
- ELISA
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- Applications:
- ELISA
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- Applications:
- ELISA
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Mouse Monoclonal to CACNG2/Stargazin
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; ICC; IF
- Conjugation:
- Unconjugated
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Mouse Monoclonal to NALCN
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; ICC; IF
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav3.1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; ICC; IF
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav beta 4
- Host Species:
- Mouse
- Species Reactivity:
- Hamster; Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav beta 1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Kv3.1
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav1.3
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav1.3
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav1.2
- Host Species:
- Mouse
- Species Reactivity:
- Hamster; Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav beta 2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Mouse Monoclonal to Cav3.2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; ICC; IF; IP; AM
- Conjugation:
- Unconjugated
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Rabbit Monoclonal Antibody to CAMKIV
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB
- Conjugation:
- Unconjugated
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Rabbit Monoclonal Antibody to CaMKI
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB; IP; ICC; FC
- Conjugation:
- Unconjugated
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Rabbit Monoclonal Antibody to Calretinin
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- IHC-Fr; IHC-P; ICC; IF
- Conjugation:
- Unconjugated
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Rabbit Monoclonal Antibody to S100
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- IHC-Fr; IHC-P
- Conjugation:
- Unconjugated
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S100 Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; Sandwich ELISA; Purification; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
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Calbindin Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; Protein Array
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
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Calretinin Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; Protein Array; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
- iNeuMab™ Rabbit Anti-Alpha-synuclein (CBP1631) (Cat#: NAB-08-PZ079)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- Mouse Anti-SCN5A Monoclonal Antibody (CBP708) (Cat#: NAB-0720-Z2720)
- NeuroMab™ Anti-GARP Antibody(NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- NeuroMab™ Anti-GD2 Antibody(NRZP-1222-ZP767) (Cat#: NRZP-1222-ZP767)
- NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P792) (Cat#: NRP-0422-P792)
- NeuroMab™ Anti-Alpha Synuclein BBB Shuttle Antibody(NRZP-1022-ZP4050) (Cat#: NRZP-1022-ZP4050)
- NeuroMab™ Anti-Alpha Synuclein Antibody(NRP-0422-P614) (Cat#: NRP-0422-P614)
- NeuroMab™ Anti-ApoC3 BBB Shuttle Antibody(NRZP-1022-ZP3503) (Cat#: NRZP-1022-ZP3503)
- NeuroMab™ Anti-TNFα BBB Shuttle Antibody(NRZP-1022-ZP4105) (Cat#: NRZP-1022-ZP4105)
- Green Fluorescent Tau SH-SY5Y cell Line (Cat#: NCL2110P219)
- Mouse Retinal Ganglion Cells (Cat#: NCL2110P145)
- Rat Retinal Muller Cell Line, Immortalized (Cat#: NCL-21P6-192)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Rat Olfactory Ensheathing Cells (Cat#: NRZP-1122-ZP162)
- Human Astrocytes, Immortalized (Cat#: NCL-2105-P182-AM)
- Rat Microglia Cell Line HAPI, Immortalized (Cat#: NCL2110P015)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Green Fluorescent Alpha-synuclein SH-SY5Y Cell Line (Cat#: NCL2110P209)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- pAAV-syn-jGCaMP8s-WPRE (Cat#: NTA-2106-P063)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)