Hydrocephalus Related Research Tools
Hydrocephalus (HC) is a condition where abnormal cerebrospinal fluid (CSF) is build up in the cavities of the brain. It is also called water in the brain. HC can be present at birth or developed in childhood or adulthood. It is divided into different categories, acquired hydrocephalus, congenital hydrocephalus, communicating hydrocephalus, non-communication hydrocephalus, normal pressure hydrocephalus and hydrocephalus ex-vacuo.
Now, little is understood about the causes of hydrocephalus. It is classically defined as a result of a dynamic imbalance between the production and absorption of CSF. The fluid accumulates in the two large lateral ventricles, resulting in an enlarged brain and skull. The accumulation of fluid eventually may cause neurological symptoms such as convulsions, intellectual disability, and epileptic seizures.
Creative Biolabs offers a wide range of tools, including specific antibodies as well as peptides and proteins targeting different biological processes of hydrocephalus. Our products are keenly sought by neuroscience researchers, particularly those applicable to studies involving hydrocephalus cause and various pathways.
Pathways Related to Hydrocephalus
| Super pathways | Genes |
| PI3K-Akt signaling pathway | PTEN, PIK3R2, FGFR3, FGFR2, CCND2, AKT3 |
| NFAT and cardiac hypertrophy | PTEN, PIK3R2, FGFR3, FGFR2, AKT3 |
| Pathways in cancer | PTEN, PIK3R2, FGFR3, FGFR2, CCND2, AKT3 |
| ErbB signaling pathway | PTEN, PIK3R2, FGFR3, FGFR2, AKT3 |
| Apoptosis pathway | PIK3R2, FGFR3, FGFR2, AKT3 |
Molecular Functions Related to Hydrocephalus
| Functions | Genes |
| Protein binding | ZIC3, WDR81, STK36, PTEN, PLOD1, PIK3R2 |
| Protein kinase activity | STK36, FGFR3, FGFR2, CCND2, AKT3 |
| Fibroblast growth factor-activated receptor activity | FGFR3, FGFR2 |
For Research Use Only. Not For Clinical Use.
Target
Premade Viruses
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iNeuMab™ Mouse Anti-NECTIN1 Monoclonal Antibody (CBP7236) [CAT#: NAB-0720-Z9716]
PVRL1/NECTIN1 Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FCM
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Bovine NEFH Monoclonal Antibody (CBP6969) [CAT#: NAB2109P332]
Anti-Neurofilament H Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Bovine
- Applications:
- IF; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Mouse Nlgn4l Monoclonal Antibody (CBP6884) [CAT#: NAB2109P229]
Anti-Neuroligin 4 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse
- Applications:
- ELISA; IF; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP6479) [CAT#: NAB-1021-R0348]
Mouse monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Rat
- Applications:
- WB; ICC; IHC; IP
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-PRKAR2A Monoclonal Antibody (CBP6243) [CAT#: NAB-1021-R0098]
Rabbit monoclonal to PRKAR2A
- Host Species:
- Rabbit
- Species Reactivity:
- Human; Mouse; Rat; Porcine
- Applications:
- WB; IHC-P; IF; IP
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-P-tau181 Monoclonal Antibody (CBP6090) [CAT#: NAB-0421-R0772]
Mouse monoclonal to P-tau181
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-HTT Monoclonal Antibody (CBP6051) [CAT#: NAB-0421-R0612]
Mouse monoclonal to HTT
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-FABP3 Monoclonal Antibody (CBP6004) [CAT#: NAB-0421-R0409]
Mouse monoclonal to FABP3
- Host Species:
- Mouse
- Species Reactivity:
- Human; Monkey; Mouse; Rat
- Applications:
- IF; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-FABP3 Monoclonal Antibody (CBP5968) [CAT#: NAB-0421-R0353]
Mouse monoclonal to FABP3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-S100B Monoclonal Antibody (CBP5937) [CAT#: NAB-0421-R0289]
Mouse monoclonal to S100B
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5898) [CAT#: NAB-0421-R0155]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-GFAP Monoclonal Antibody (CBP5872) [CAT#: NAB-0421-R0126]
Mouse monoclonal to GFAP
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IF; IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5845) [CAT#: NAB-0421-R0038]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-UCHL1 Monoclonal Antibody (CBP5820) [CAT#: NAB-0421-R0011]
Mouse monoclonal to UCHL1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP5309) [CAT#: NAB-0321-R0759]
Mouse Monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IF; IHC; WB
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-Amyloid Beta Monoclonal Antibody (CBP5258) [CAT#: NAB-0321-R0554]
Mouse Monoclonal to Amyloid Beta
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
iNeuMab™ Mouse Anti-XTRP Monoclonal Antibody (CBP5220) [CAT#: NAB-2103-P1129]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-UNC45 Monoclonal Antibody (CBP5194) [CAT#: NAB-2103-P1073]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Testican Monoclonal Antibody (CBP5161) [CAT#: NAB-2103-P1013]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Sarcoplasmic Reticulum Monoclonal Antibody (CBP5119) [CAT#: NAB-2103-P942]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Shank Monoclonal Antibody (CBP5086) [CAT#: NAB-2103-P893]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Presenilin Monoclonal Antibody (CBP5047) [CAT#: NAB-2103-P814]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-PACSIN Monoclonal Antibody (CBP5008) [CAT#: NAB-2103-P750]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-NP Monoclonal Antibody (CBP4977) [CAT#: NAB-2103-P701]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-NGFR Monoclonal Antibody (CBP4941) [CAT#: NAB-2103-P655]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-neurolysin Monoclonal Antibody (CBP4910) [CAT#: NAB-2103-P597]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP
iNeuMab™ Mouse Anti-netrin-1 Monoclonal Antibody (CBP4881) [CAT#: NAB-2103-P545]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Myelin Monoclonal Antibody (CBP4849) [CAT#: NAB-2103-P498]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
iNeuMab™ Mouse Anti-LNX Monoclonal Antibody (CBP4815) [CAT#: NAB-2103-P443]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
iNeuMab™ Mouse Anti-Gl Syn Monoclonal Antibody (CBP4759) [CAT#: NAB-2103-P344]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; ELISA
Product
Hot Products
Antibodies
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2293) (Cat#: NRP-0422-P2293)
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- NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P792) (Cat#: NRP-0422-P792)
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- NeuroMab™ Anti-Alpha Synuclein BBB Shuttle Antibody(NRZP-1022-ZP4050) (Cat#: NRZP-1022-ZP4050)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- iNeuMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
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Cells
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Human Dental Pulp Stem Cells (Cat#: NRZP-1122-ZP113)
- Human Astrocytes, Immortalized (Cat#: NCL-2105-P182-AM)
- Human Neurons Isolated from Cortex (Cat#: NCL-21P6-023)
- Green Fluorescent BACE1 Cell Lines (Cat#: NCL2110P214)
- Mouse Retinal Ganglion Cells (Cat#: NCL2110P145)
- Mouse Glioma Cell Line GL261 (Cat#: NCL-2108P28)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- Rat Schwann Cells RSC96, Immortalized (Cat#: NCL-2108P21)
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Kits
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
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Tracers
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- Dextran, NHS Activated, 40 kDa (Cat#: NRZP-0722-ZP124)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA (Cat#: NTA-2010-TT342)
- pAAV-syn-jGCaMP8s-WPRE (Cat#: NTA-2106-P063)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
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Gene Related Products
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
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Biospecimens
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
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Cell Assay Reagents
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
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