Neuron Products

Neurons represent the fundamental building blocks of both the structure and function of the nervous system. Neurons are characterized by their long synapses (axons) and cell bodies and cell processes, which facilitate the study of pathological processes associated with various central nervous system (CNS) diseases. Based on their functions, neurons can be classified into three main categories: sensory neurons, motor neurons, and interneurons. Each type of neuron plays a distinct role within the nervous system. For instance, sensory neurons are responsible for receiving external stimuli, motor neurons control muscle contraction, and interneurons transmit information in neural circuits.

At Creative Biolabs, our neuronal products are derived from high-quality brain tissues, which undergo a rigorous screening and culturing process to ensure their purity and activity. We offer a comprehensive range of neuronal products, including primary animal neurons (from rat, mouse, and rabbit), human primary neurons, and human induced pluripotent stem (hiPSC) cell-derived neurons. To learn more about our products, or to submit a project request, contact us today.

Product Overview Product Features Applications Usage Guidelines Related Products

Product Overview

	Primary Neurons Human Neurons derived from the cerebral cortex, hippocampus, cerebellum, midbrain, brainstem, and hypothalamus. Mouse Neurons derived from different brain regions of postnatal or embryonic CD1 (ICR) mouse or C57BL/6 mouse. Rat Neurons derived from different brain regions of postnatal or embryonic SD Rat. Rabbit Neurons derived from different brain regions of rabbit.
	Human iPSC-derived Neurons iNeu™ Human Sensory Neurons iNeu™ Human Motor Neurons iNeu™ Human Cortical Neurons iNeu™ Human Dopamine Neurons iNeu™ Human Glutamatergic Neurons
	Immortalized Neurons Our immortalized neurons are achieved through genetic engineering, using retroviruses to introduce oncogenes such as SV40 T antigen or myc gene into neural stem cells, thereby achieving immortality.

Product Features

High Purity: Our neuronal cell products are of the highest purity, exceeding 90%. They are free from HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, among other contaminants.
Terminal Differentiation: Neurons are terminally differentiated cells with weak proliferation ability and are recommended to be used directly in experiments.
Adherent Culture: Neuronal cells are cultured in an irregular adherent manner, which is an optimal choice for long-term research in a laboratory setting.

Applications

Basic Research: Neurons from Creative Biolabs are suitable for basic research in neuroscience, including the study of neuronal differentiation, migration, and signal transduction mechanisms.
Disease Models: Neurons from Creative Biolabs can be used to model diseases of the nervous system in vitro and to study the molecular mechanisms of disease onset and development.
Drug Screening: Neurons from Creative Biolabs can be used as a drug screening platform to evaluate the potential efficacy and toxicity of new drugs on the nervous system.

Usage Guidelines

Culture Medium Selection: It is recommended that a dedicated complete culture medium, such as the neuronal cell-specific complete culture medium from Creative Biolabs, be used to ensure optimal cell growth.
Transportation and Storage: The product is shipped frozen and must be thawed and cultured according to specific steps upon receipt to ensure cell activity.
Experimental Operation: All cell operations must be performed in a Class II biosafety bench. Waste fluid and utensils must be sterilized before disposal.

For further information or to place an order, please contact us. We provide professional technical support and customized services to meet your scientific research needs.

References

Zabolocki, Michael, et al. "BrainPhys neuronal medium optimized for imaging and optogenetics in vitro." Nature communications 11.1 (2020): 5550.
Robinson, Edward J., et al. "Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1." Cell death discovery 4.1 (2018): 107.
Distributed under Open Access license CC BY 4.0 without modification.

For Research Use Only. Not For Clinical Use.

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