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Creative Biolabs

Sodium Channel Related Research Reagents

Sodium Channels

Sodium channels are intact membrane proteins that can form membrane ion channels, allowing sodium ion to be conducted through the plasma membrane of cells. In excitable cells such as nerve cells, muscle cells, and certain types of glia, sodium channels are responsible for the rising phase of action potentials. Sodium channels are the molecular targets of drugs used to prevent acute pain and to treat arrhythmia, epilepsy, and bipolar disorder. Sodium channel blockers are also being developed for the treatment of chronic pain.

Sodium channels are classified according to their gating mechanism. There are two very different types:

Voltage-gated sodium channel (NaV): NaV opens by responding to membrane depolarization, allowing sodium to enter, and causing depolarization to propagate along the plasma membrane of nerves, muscles, and other electrically stimulated cells. NaV is present in the membrane of most excitable cells and exists as a heterodimer or heterotrimer in the form of 1α- and 1 or 2β-subunits. They play a role in many processes, such as feelings, emotions, thoughts and movements.

Epithelial sodium channel (ENaC): ENaC is present in the absorbent epithelium, such as the distal renal tubules, alveolar epithelium, and distal colon. It is responsible for sodium reabsorption. They exist in the form of heterotetramers of α-, β- and γ-subunits, mainly 2α:1β:1γ. ENaC is involved in various biological processes, including sodium homeostasis, salty taste, nociception, pain transduction, tactile and mechanical transduction.

Sodium ion channel research requires a series of scientific research products. Creative Biolabs has been devoted to the research and development of the most advanced reagents to assist ion channel research. Our product portfolio covers a complete list of sodium channel activators and blockers, monoclonal antibodies, labeled antibodies, proteins and assay kits.

Please browse the options to take a deeper look at the tools for your research needs.

For Research Use Only. Not For Clinical Use.

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Epithelial Sodium Channel (ENaC) Related Research Reagents

Voltage-Gated Sodium Channel Related Research Reagents

Related Products
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nNav1.5 Mouse Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
ICC; IF; WB; FC
Conjugation:
Unconjugated
Mouse Anti-NALCN (CBP5757) [CAT#: NAB2105290SL]

Anti-NALCN Polyclonal Antibody [FITC]

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; ICC; IF
Conjugation:
FITC

Mouse Monoclonal [NS134-12] to Nav1.8

Host Species:
Mouse
Species Reactivity:
Human; Monkey; Mouse; Rat
Applications:
WB; IHC; ICC; IF; AM
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

Mouse Monoclonal [NS187-7] to NALCN

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; ICC; IF
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

Mouse Monoclonal [14E10] to ENaC alpha

Host Species:
Mouse
Species Reactivity:
Mouse; Rat
Applications:
WB; IHC
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

Mouse Monoclonal [2G4] to ENaC alpha

Host Species:
Mouse
Species Reactivity:
Mouse; Rat
Applications:
WB; IHC
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1605

Mouse Monoclonal [NS396-29] to Nav beta3

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; ICC; IF
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

Mouse Monoclonal [NS395-68] to Nav beta2

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB; IHC; ICC; IF
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

Mouse Monoclonal [16E4] to ENaC Beta

Host Species:
Mouse
Species Reactivity:
Mouse; Rat
Applications:
WB
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1598

Mouse Monoclonal [NS271-44] to ASIC1

Host Species:
Mouse
Species Reactivity:
Mouse; Rat
Applications:
WB; IHC; ICC; IF
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

Mouse Monoclonal [NS68-6] to Nav1.7

Host Species:
Mouse
Species Reactivity:
Hamster; Human; Mouse; Rat
Applications:
WB; ICC; IF; IP; AM
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

HCN1 Rat Monoclonal Antibody

Host Species:
Rat
Species Reactivity:
Mouse; Rat; Human
Applications:
IHC-P; WB
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 852

ASIC1 Mouse Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat; Human
Applications:
WB; ICC; IF
Conjugation:
Unconjugated

ASIC2 Rabbit Monoclonal Antibody

Host Species:
Rabbit
Species Reactivity:
Mouse; Rat; Human
Applications:
WB
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 851

ATP1A3 Rabbit Monoclonal Antibody

Host Species:
Rabbit
Species Reactivity:
Mouse; Rat; Human
Applications:
WB
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 850

ATP1A3 Rabbit Monoclonal Antibody

Host Species:
Rabbit
Species Reactivity:
Mouse; Rat
Applications:
IP; WB; ICC; IF
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 849

Stomatin Rabbit Monoclonal Antibody

Host Species:
Rabbit
Species Reactivity:
Human
Applications:
WB; ICC; IF; IP; FC
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 848

Nav1.7 Mouse Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
ICC; IF; IP; IHC-P; IHC-Fr; FC
Conjugation:
Unconjugated

Stomatin Rabbit Monoclonal Antibody

Host Species:
Rabbit
Species Reactivity:
Mouse; Rat; Human
Applications:
WB; ICC; IF; IP; FC
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 847

HCN1 Mouse Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
IHC-P; IHC-Fr; IP; WB; ICC; IF; FC
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 846
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