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Creative Biolabs
Product

Human P2RY6 β-Arrestin GPCR Cell Line [CHO-K1]

[CAT#: NCL-7P995]

Species:
Human
Applications:
GPCR Screening
Cell Types:
GPCR Cell

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Product Overview

Description

The β-Arrestin orphan GPCR cell line NCL-7P995 at Creative Biolabs is engineered to co-express PK-labeled GPCR and enzyme receptor (EA) labeled β-Arrestin. Activation of GPCR-PK induces the recruitment of β-Arrestin-EA, forcing the two β-galactosidase fragments (EA and PK) to complement each other.

Features

Coupling: Gq
β-Arrestin isoform: β-arrestin-2
Tag: ARMS2-PK2
Agonist/Ligand: Uridine 5'-(trihydrogen diphosphate)

Cell Types

GPCR Cell

Cell Location

β-Arrestin

Applications

GPCR Screening

Assay

GPCR Screening Assay

Readout

β-Arrestin

Assay Characteristics

Coupling: Gq
β-Arrestin isoform: β-arrestin-2
Tag: ARMS2-PK2
Agonist/Ligand: Uridine 5'-(trihydrogen diphosphate)

Species

Human
Properties

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

P2RY6

Official Name

P2RY6

Alternative Names

NRU; P2P; P2Y purinoceptor 4; P2Y4; UNR; pyrimidinergic receptor P2Y; G-protein coupled; 4; uridine nucleotide receptor
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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