NeuroMab™ Anti-CTNNB1 BBB Shuttle Antibody, Clone 12H7

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

12H7

Applications

ELISA; WB; IHC

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CTNNB1

Official Name

CTNNB1

Full Name

Catenin β-1

Alternative Names

CTNNB1; CTNNB; MRD19; armadillo; catenin beta 1; EVR7; NEDSDV

Product Pictures

Figure 1 is the Western blot results of monoclonal antibody 12H7 in 9 different clones;

IHC

Figure 2 is the expression of β-Catenin protein in pancreatic tissue detected by immunohistochemical method using monoclonal antibody 12H7 as the primary antibody;

IHC

Figure 3 is the expression of β-Catenin protein in endometrial tissue detected by immunohistochemical method using monoclonal antibody 12H7 as the primary antibody;

IHC

Figure 4 shows the expression of β-Catenin protein in prostate tissue detected by immunohistochemical method using monoclonal antibody 12H7 as the primary antibody.

Publications