NeuroMab™ Anti-FGFR1 BBB Shuttle Antibody, Clone #A08
- Host Species:
- Rat
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; In Vitro; In Vivo; ADCC; Antagonist
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1A depicts the binding sensorgrams of mAb #A08 and buffer to FGFR1-IIIb and -IIIc, FGFR2 and FGFR3 The binding signal (response units, RU) is plotted over time. Buffer control and mAb #A08 were tested for binding to huFGFR1b-IIIb, -IIIc, huFGFR2 and huFGFR3.
Figure 1B depicts the binding sensorgrams of mAb #A08 and buffer to FGFR1-IIIb and -IIIc, FGFR2 and FGFR3 The binding signal (response units, RU) is plotted over time. Buffer control and mAb #A08 were tested for binding to huFGFR1b-IIIb, -IIIc, huFGFR2 and huFGFR3.
Figure 2 shows the mapping of mAb #A08, mAb #A05, and a control antibody (anti-egg lysozyme) to the domain of lg-D2 by ELISA. The optical density measured at 450 nm was plotted against antibody concentration (using the Logio scale).
Figure 3A shows the binding of various affinity matured mAbs to human FGFRI b (1Mb) (hFGFRI b-IIIb) and human FGFRI b (IIIc) (hFGFRI b-IIIc) measured by ELISA.
A) mAbs are in lgG1 format,
Figure 3B shows the binding of various affinity matured mAbs to human FGFRI b (1Mb) (hFGFRI b-IIIb) and human FGFRI b (IIIc) (hFGFRI b-IIIc) measured by ELISA.
B) mAbs are in monovalent SEEDbody format.
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