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Creative Biolabs
Product

NeuroMab™ Anti-IL-1R1 BBB Shuttle Antibody, Clone antibody 6

[CAT#: NRZP-1022-ZP2861]

Host Species:
Human
Species Reactivity:
Human; Cynomolgus Monkey
Applications:
Block; Inhib; In Vivo; In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Immunogen

chimeric human / mouse IL-1R1 extracellular sites

Species Reactivity

Human; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Human

Clone Number

antibody 6

Applications

Block; Inhib; In Vivo; In Vitro
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

IL-1R1

Official Name

IL1R1

Full Name

Interleukin 1 receptor, type I

Alternative Names

IL1R1; CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80; Interleukin 1 receptor; type I; interleukin 1 receptor type 1
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For Research Use Only. Not For Clinical Use.
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