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Creative Biolabs
Product

NeuroMab™ Anti-Oligomeric tau BBB Shuttle Antibody, Clone M204

[CAT#: NRZP-1222-ZP1196]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Inhib; Block; In Vitro

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Product Overview

Description

Soluble oligomers of aggregated tau accompany the accumulation of insoluble amyloid fibrils, a histological hallmark of Alzheimer disease (AD) and two dozen related neurodegenerative diseases. The mAb (M204) that binds oligomeric tau, but not tau monomers or fibrils. M204 and an engineered single-chain variable fragment (scFv) inhibited seeding by IL15-induced tau oligomers and pathological extracts from donors with AD and chronic traumatic encephalopathy.

Species Reactivity

Human

Host Species

Mouse

Clone Number

M204

Applications

Inhib; Block; In Vitro
Target

Target

Oligomeric tau
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