Product
NeuroMab™ Anti-SCN9A BBB Shuttle Antibody, Clone 15C8
[CAT#: NRZP-1022-ZP3510]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; Inhib; In Vitro; In Vivo; Antagonist
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Immunogen
A peptide (1418-SVNVDKQPKYEYSL corresponding to domain C and E3 extracellular loop C terminal regions of human Nav1.7 (UniProtKB/Swiss-Prot:Q15858) was selected as an antigen.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG
Clone Number
15C8
Applications
WB; ELISA; Inhib; In Vitro; In Vivo; Antagonist
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
SCN9A
Official Name
SCN9A
Full Name
sodium voltage-gated channel alpha subunit 9
Alternative Names
SCN9A; ETHA; FEB3B; GEFSP7; HSAN2D; NE-NA; NENA; Nav1.7; PN1; SFNP; sodium voltage-gated channel alpha subunit 9
Product Pictures
FuncS
Figure 1 Evaluation of drug efficacy of local drug administration on the sole of the foot in the partial ligation model of sciatic nerve
FuncS
Figure 2 Drug efficacy evaluation of intravenous administration in partial sciatic nerve ligation model
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
