Product
NeuroMab™ Anti-SORT1 Antibody, Clone S-60-15.1
[CAT#: NRP-0422-P1322]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- In Vitro; In Vivo; Block
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The monoclonal anti-Sortilin antibody which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, the antibody can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Clone Number
S-60-15.1
Applications
In Vitro; In Vivo; Block
Product Properties
Preservatives
BSA Free
Concentration
1mg/mL
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
SORT1
Official Name
SORT1
Full Name
Sortilin
Alternative Names
SORT1; Gp95; LDLCQ6; NT3; NTR3; Sortilin 1
Product Pictures
Inhib
Figure 1 shows the dose-dependent inhibition of biotinylated progranulin binding to soltilin-expressing cells by anti-soltilin antibodies.
Inhib
Figure 2 shows the cell surface expression levels of saltylin after 72 hours of incubation with anti-saltillin antibody.
Inhib
Figure 3 shows the measurement of mouse progranulin (PGRN) protein levels in mouse plasma samples at different times after injection of anti-saultyrin antibody.
WB
Figure 4 shows the measurement of saltyrin protein levels using Western blot analysis of mouse-derived leukocyte lysates.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
