NeuroMab™ Anti-TNFα Antibody, Clone cA2
A functional antibody raised against Human TNFα.
- Host Species:
- Chimeric
- Species Reactivity:
- Human
- Applications:
- ELISA; Neut; Block; Inhib; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 is a graph showing the dose-dependent binding of mouse mAb A2 to human TNF[alpha].
Figure 2 is a graph showing the neutralizing effect of murine A2 on TNF cytotoxicity in vitro.
Figure 3 shows that mAb A2 inhibits or neutralizes TNF produced by chimpanzee monocytes and rhTNF[alpha].
Figure 4 is a graph showing the neutralizing effect of chimeric A2 on TNF cytotoxicity.
Figure 5 shows the results of a cross-blocking epitope ELISA for mouse A2 (mA2).
Figure 6 is a graph showing the in vitro neutralization of TNF-induced ELAM-1 expression by chimeric A2. The control is a chimeric mouse/human IgG1 anti-CD4 antibody.
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