Product
NeuroMab™ Anti-UNC5B Antibody,Clone NR4066P
[CAT#: NRP-0422-P1931]
Functional antibody against Human Unc5B
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; FC; In Vitro; Block; In Vivo
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The anti-Unc5B antibody can be used to modulate angiogenesis and treat or prevent disorders associated with abnormal angiogenesis.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Clone Number
NR4066P
Applications
WB; ELISA; FC; In Vitro; Block; In Vivo
Relevant Diseases
Parkinson's Disease
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
UNC5B
Official Name
UNC5B
Full Name
Unc-5 Netrin Receptor B
Alternative Names
Unc-5 Netrin Receptor B; P53-Regulated Receptor For Death And Life Protein 1; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; P53RDL1; UNC5H2; Transmembrane Receptor Unc5H2;
Gene ID
60630(Rat)
Uniprot ID
O08722(Rat)
Product Pictures
FuncS
Figure 2 illustrates corneal micropocket assay data from postnatal day 5 mice treated with anti-Unc5B demonstrating that antibody treatment results in increased corneal neovascularization.
Representative images of FITC-dextran-stained corneas with and without antibody treatment are shown.
FCM
Figure 1 illustrates binding curve data demonstrating that anti-Unc5B antibodies interfere with Netrin-1 binding to Unc5B.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
