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Creative Biolabs
Product

Mouse Anti-AR Monoclonal Antibody (CBP2843)

[CAT#: NAB20101920CR]

Mouse Monoclonal (1F7C12) to AR

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB; ELISA

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Product Overview

Description

AR belongs to the nuclear hormone receptor family and NR3 subfamily. AR is a ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. AR is activated, but not phosphorylated, by HIPK3. Defects in AR are the cause of androgen insensitivity syndrome (AIS), previously known as testicular feminization syndrome (TFM), which is an X-linked recessive form of pseudohermaphroditism due end-organ resistance to androgen. Defects in AR are the cause of spinal and bulbar muscular atrophy X-linked type 1 (SMAX1) which also known as Kennedy disease.

Expression Host

Mammalian cells

Immunogen

AR fusion protein Ag17291

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2843

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neuron

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

AR

Official Name

AR

Full Name

Androgen receptor

Alternative Names

Androgen receptor splice variant 3;
AR-V7;
AR-V7(AR3);
AR3;
ARv7;
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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