NeuroMab™ Anti-EGFR domain III, Mouse Monoclonal Antibody, Clone h-R3 (CBP8817)

[CAT#: NRZP-0522-ZP206]

Host Species:: Human

Species Reactivity:: Human

Applications:: Block; FC; IHC

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Product Overview

Description

Human anti-Epidermal growth factor receptor domain III (EGFR domain III) Recombinant Antibody (Unconjugated), suitable for Block, FC, IHC.

Immunogen

This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.

Species Reactivity

Human

Clonality

Recombinant

Host Species

Human

Isotype

IgG1, kappa

Clone Number

CBP8817

Applications

Block; FC; IHC

Application Notes

This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor.

Conjugation

Unconjugated

Product Properties

Form

Liquid. PBS with 0.02% Proclin 300.

Concentration

1 mg/mL

Purity

Purified antibody, via affinity chromatography

Shipping

2-8°C (on cold packs)

Storage

Store at 2-8°C for up to 1 month. For longer storage, aliquot and store at -20_C. Avoid mulitiple freeze thaw cycles.

Research Use Only

For research use only.

Target

EGFR domain III

Full Name

Epidermal growth factor receptor domain III (EGFR domain III)

Alternative Names

ERBB-D3; ERBB1; HER1; PIG61; mENA; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor