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Creative Biolabs
Product

NeuroMab™ Anti-Amyloid Beta 1-40 BBB Shuttle Antibody, Clone 1A10

[CAT#: NRZP-1022-ZP3650]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; ELISA; In Vitro; IHC

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Clone Number

1A10

Applications

WB; ELISA; In Vitro; IHC
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

Amyloid Beta 1-40

Official Name

Amyloid Beta 1-40

Full Name

Amyloid beta

Alternative Names

APP; Aβ; Abeta; Amyloid β
Product Pictures
WB

Figure 1 Confirmation of the specificity of the 1A10 antibody by Western Blotting.

It was confirmed that monoclonal antibody 1A10 does not react with amyloid β(1-42) and amyloid β(1-43), and recognizes only amyloid β(1-40).

ELISA

Figure 2 is the result of measuring the synthesis of β-amyloid (1-40) using a combination of 1A10 antibody and HRP-labeled 82E1 antibody.

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For Research Use Only. Not For Clinical Use.
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