NeuroMab™ Anti-GARP BBB Shuttle Antibody, Clone MHGARP8
- Host Species:
- Mouse
- Species Reactivity:
- Human; Cynomolgus Monkey
- Applications:
- FC; Inhib; Block; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 Inhibition of human Treg function by anti-hGARP in vivo.
Figure 2 MHGARP8 inhibits production of active TGF-β by human Treg clones.
Figure 3 Insufficient presentation of hTGF-β1 on the cell surface for binding by MHGARP8. 293T cells were transfected as indicated below, stained with anti-hLAP antibody or MGARP8, and analyzed by flow cytometry.
Figure 4 MHGARP8 inhibits Treg function in vivo. On day 0, designated groups of NSG mice received intravenous injections. Human PBMC were injected with or without human Tregs.
Figure 5 MHGARP8 and LHG-10 inhibit human Treg from producing active TGF-β.
Figure 6 MHGARP8 and LHG-10 inhibit the suppressive activity of human Tregs in vitro.
Figure 7 MHGARP8 and LHG-10 inhibit the suppressive activity of human Tregs in vitro.
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