Tel:
Fax:
Email:
Creative Biolabs
Product

NeuroMab™ Anti-NRP1B Antibody, Clone IRCR-101 (3H10)

[CAT#: NRP-0422-P1905]

Functional antibody against Human NRP1B

Host Species:
Human
Species Reactivity:
Human
Applications:
FC; ELISA; Inhib; In Vitro; In Vivo

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Inquiry

SPECIFIC INQUIRY

inquiry
Size:
Conjugation:
Endotoxin:
Purity:
Engineering:
Product Overview

Description

The antibody is designed against NRP1 (Neuropilin 1) and useful for preventing or treating cancer.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Clone Number

IRCR-101 (3H10)

Applications

FC; ELISA; Inhib; In Vitro; In Vivo
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

NRP1B

Official Name

NRP1B

Alternative Names

Neuropilin
Product Pictures
SDS-PAGE

Figure 1 shows the Coomassie staining of each purified scFv antibody fragment.

FuncS

Figure 10 shows the results of the inhibitory effect of IRCR-101 (3H10) on neovascularization in a subcutaneous model of glioblastoma.

FuncS

Figure 11 shows the results of changes in signal elements involved in IRCR-101 processing.

FuncS

Figure 12 shows the distribution of IRCR-101 in an orthotopic model of glioma cell lines.

ELISA

Figure 2 shows the results of an ELISA showing the binding ability of three anti-NrP1 scFv antibodies to NRP1.

ELISA

Figure 3 shows the results of ELISA showing the binding ability to NRP1 according to the concentration of three anti-NRP1 antibody fragments.

IF

Figure 4 is a confocal laser scanning micrograph showing the internalization function of three anti-NrP1 scFv antibodies.

Inhib

Figure 5 shows the results of inhibition of cell migration of anti-NrP1 scFv antibody fragments using the U87MG cell line.

Inhib

Figure 6 shows the purity of production of the three anti-NRP1 IgG antibodies.

FCM

Figure 7 shows the results of cancer cell-specific internalization using FACS.

FuncS

Figure 8 shows the binding activity of IRCR-101(3H10) against cancer-specific NRP1 in a xenograft model of glioma cell lines.

FuncS

Figure 9 shows the binding ability of IRCR-101 (3H10) to cancer-specific NRP1 in glioblastoma patient samples.

Publications

Publications (0)

gift-card

Related Products
For Research Use Only. Not For Clinical Use.
Send Inquiry Send Inquiry
Inquiry Basket
compare

Send inquiry