NeuroMab™ Anti-NRP1B Antibody, Clone IRCR-101 (3H10)
Functional antibody against Human NRP1B
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- FC; ELISA; Inhib; In Vitro; In Vivo
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Endotoxin Level
Low Endotoxin < 1 EU/mg
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Research Use Only
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Figure 1 shows the Coomassie staining of each purified scFv antibody fragment.
Figure 10 shows the results of the inhibitory effect of IRCR-101 (3H10) on neovascularization in a subcutaneous model of glioblastoma.
Figure 11 shows the results of changes in signal elements involved in IRCR-101 processing.
Figure 12 shows the distribution of IRCR-101 in an orthotopic model of glioma cell lines.
Figure 2 shows the results of an ELISA showing the binding ability of three anti-NrP1 scFv antibodies to NRP1.
Figure 3 shows the results of ELISA showing the binding ability to NRP1 according to the concentration of three anti-NRP1 antibody fragments.
Figure 4 is a confocal laser scanning micrograph showing the internalization function of three anti-NrP1 scFv antibodies.
Figure 5 shows the results of inhibition of cell migration of anti-NrP1 scFv antibody fragments using the U87MG cell line.
Figure 6 shows the purity of production of the three anti-NRP1 IgG antibodies.
Figure 7 shows the results of cancer cell-specific internalization using FACS.
Figure 8 shows the binding activity of IRCR-101(3H10) against cancer-specific NRP1 in a xenograft model of glioma cell lines.
Figure 9 shows the binding ability of IRCR-101 (3H10) to cancer-specific NRP1 in glioblastoma patient samples.
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