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Creative Biolabs
Product

NeuroMab™ Anti-NRP1B Antibody, Clone NR176P

[CAT#: NRP-0422-P1907]

Functional antibody against Human NRP1B

Host Species:
Humanized
Species Reactivity:
Human
Applications:
FC; ELISA; Inhib; In Vitro; In Vivo

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Product Overview

Description

The antibody is designed against VEGF that inhibits binding of a vascular endothelial growth factor (VEGF) to neuropilin-1 (NRP1). The antibody against VEGF that inhibits binding of VEGF to NRP1.

Immunogen

Human recombinant VEGF165

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Humanized

Clone Number

NR176P

Applications

FC; ELISA; Inhib; In Vitro; In Vivo
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

NRP1B

Official Name

NRP1B

Alternative Names

Neuropilin
Product Pictures
ELISA

Figure 1 is the analysis result of the ability of the antibody to inhibit the binding of VEGF to NRP1.

In Vivo

Figure 10 shows the results of examining the binding ability of KLHc161HC, which is the humanized chimeric antibody, to VEGF165, VEGF121 and VEGF165b.

Inhib

Figure 2 shows the results of examining the inhibitory effect of KLHc161, which is the antibody, on cell proliferation.

Inhib

Figure 3 shows the results of examining the inhibitory effect of KLHc161, which is the antibody, on cell proliferation.

In Vivo

Figure 4 shows the results of examining the in vivo inhibitory effect of KLHc161, which is the antibody, on tumor growth.

In Vivo

Figure 5 shows the results of examining the inhibitory effect of KLHc161, which is the antibody, on angiogenesis in a CNV model.

In Vivo

Figure 6 shows the results of investigation of the tumor growth inhibitory effect of the humanized chimeric antibody KLHc161HC.

In Vivo

Figure 7 shows the results of testing the cross-reactivity of the caninized chimeric antibody KLHc161CC with human and canine VEGF.

In Vivo

Figure 8 shows the results of examining the in vivo inhibitory effect of the caninized chimeric antibody KLHc161CC on tumor growth in human cell lines.

In Vivo

Figure 9 shows the results of examining the in vivo inhibitory effect of the caninized chimeric antibody KLHc161CC on tumor growth in canine cell lines.

Publications

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For Research Use Only. Not For Clinical Use.
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