Product
NeuroMab™ Anti-TNFα Antibody, Clone MAb 32
[CAT#: NRP-0422-P786]
A functional antibody raised against Human TNFα.
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; Cyt; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The antibody binds to human tumor necrosis factor alpha (TNF) and is useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Clone Number
MAb 32
Applications
ELISA; Cyt; In Vitro; In Vivo
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
>95% by SDS PAGE or HPLC
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Product Pictures
Cyt
Figure 1 shows the effect of anti-TNF mAbs 1 and 32 on TNF cytotoxicity in WEHI-164 cells.
FuncS
Figure 2 shows the enhancement of TNF reversion activity by MAb 32.
FuncS
Figure 3 shows the potentiation of TNF-induced tumor regression by MAb 32 - day 1 dose response.
FuncS
Figure 4 shows the binding of radiolabeled TNF to receptors on bovine aortic endothelial cells.
FuncS
Figure 5 shows the receptor binding studies of TNF complexed with MAb 32 (—◆—), control antibody and MAb 47 (—▪—) against the melanoma cell line MM418E.
FuncS
Figure 6 shows the effect of MAb 32 (▪) control MAb and MAb 47 (*) on TNF-mediated tumor regression in vivo.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
