NeuroMab™ Anti-Amyloid Beta 1-42 BBB Shuttle Antibody, Clone 8C5
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Storage
Research Use Only
Target
Official Name
Full Name
Alternative Names
Figure 1 illustrates the selectivity of 8C5 for globulomers versus Aß(1-42) monomers, Aß(1-40) and sAPP. The selectivity factor for 8C5 can be calculated as the ratio between EC50 values (relative to Aβ(1-42) monomer in HFIP 2346/568.2=4.1; relative to Aß(1-42) monomer in NH4OH > 100; relative to Aβ (1-40 ) monomer >100; relative to sAPP >100)
Figure 2 shows the binding of different concentrations of antibodies to the neocortex cross-sections of Alzheimer's disease (AD) patients or aged APP transgenic mice.
Figure 5 illustrates the quantification of the analysis of Aβ plaque staining in histological images using image analysis. Density values were calculated by subtracting the gray value of the background tissue from the gray value of the plaque (0% = no staining).
Publications (0)
