NeuroMab™ Anti-IGF1R BBB Shuttle Antibody, Clone EM164
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; FC; Inhib; In Vivo; In Vitro
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 shows fluorescence activated cell sorting (FACS) analysis of purified EM164 antibody specific binding to cells overexpressing human Y1251F IGF-I receptor or human insulin receptor.
Figure 2 shows the inhibitory effect of EM164 antibody on the binding of biotinylated IGF-I to human breast cancer MCF-7 cells.
Figure 3 shows the effect of EM164 antibody on the growth and survival of MCF-7 cells under different growth conditions, evaluated by MTT assay.
Figure 4 shows the effect of treatment with EM164 antibody, paclitaxel or a combination of EM164 antibody and paclitaxel on the growth of mouse Calu-6 lung cancer xenografts.
Figure 5 shows competition of humanized EM164 antibody (v.1.0) binding with murine EM164 antibody.
Figure 6 shows the effect of EM164 antibody on the growth and survival of MCF-7 cells at different serum concentrations.
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