NeuroMab™ Anti-IGF1R Antibody, Clone h7C10
- Host Species:
- Humanized
- Species Reactivity:
- Human
- Applications:
- FC; In Vitro; In Vivo
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Low Endotoxin < 1 EU/mg
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Research Use Only
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Figure 1 In vivo effects of monoclonal antibody 7C10 on MCF-7 tumor growth in nude mice.
Figure 2 Comparative study of the effects of MAb 7C10 and tamoxifen on the growth of tumor MCF-7 in vivo.
Figure 3 Antitumor activity of mouse antibody 7C10 in tumor cell xenograft model in vivo.
Figure 4 Comparative study on the antitumor effect of MAb 7C10 and vinorelbine (vinorelbine), and the synergistic effect of the two compounds on the growth of A549 cell line in vivo.
Figure 5 Comparison of mouse 7C10 and chimeric C7C10 MAbs inhibiting IGF1 proliferation in MCF-7 cells in vitro. Antibody 9G4 is the murine IgG1 isotype used as an experimental control.
Figure 6 Effects of 7C10 and h7C10 MAbs (humanized 1, written here as 7H2HM) on IGF1-induced signaling.
Figure 7. Comparative effects of 7C10 and h7C10 MAbs (humanized 1, written here as 7H2HM) on an in vitro model of IGF1-induced proliferation of MCF-7 cells.
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