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NeuroMab™ Anti-IL-6 Antibody, Clone NR87P
Functional antibody against Human IL-6
- Host Species:
- Humanized
- Species Reactivity:
- Human
- Applications:
- In Vitro; In Vivo; Inhib; Antagonist
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Species Reactivity
Clonality
Host Species
Clone Number
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 is a graph illustrating experimental results of IVT administration of an anti-IL-6 antibody in a rat CNV model.
Anti-VEGF antibody was administered as a positive control and the negative control was vehicle alone, p = 0.0054 on Day 15 and p = 0.0005 on Day 22 for anti-IL-6 vs. vehicle control.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0623-1P905-1.png)
Figure 2 is a graph illustrating the results of a binding experiment testing the ability of the murine 64 antibody to inhibit the binding of IL-6/IL-6R to gp130.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0623-1P905-2.png)
Figure 3 is a graph illustrating an experiment in which the ability of 020 to block IL-6 signaling was tested in the absence of excess soluble IL-6Ra.
Experiments were performed in HEK-Blue-IL-6 cells with 0.2 ng/mL IL-6 and 2pg/mL IL6Ra.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0623-1P905-3.png)
Figure 4 is a graph illustrating an experiment in which the ability of 020 to block IL-6 signaling was tested in the absence of excess soluble IL-6Ra.
Experiments were performed in HEK-Blue-IL-6 cells with 0.2 ng/mL IL-6 and 2pg/mL IL6Ra.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0623-1P905-4.png)
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