NeuroMab™ Anti-ITGAM ITGAX BBB Shuttle Antibody,Clone NR3682P

[CAT#: NRZP-1022-ZP4044]

Host Species:: Human

Species Reactivity:: Rat

Applications:: FC

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Human

Isotype

IgG1

Clone Number

NR3682P

Applications

Relevant Diseases

Neuroinflammation

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

ITGAMITGAX

Official Name

ITGAM; ITGAX

Full Name

Integrin alpha M/Integrin, alpha X

Alternative Names

ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M; ITGAX; CD11C; SLEB6; integrin subunit alpha X
; ITGAM; ITGAX; Leukocyte adhesion glycoprotein p150;95 α chain (Leukocyte adhesion receptor p150;95); RGD1561123; CR-3 α chain; Cell surface glycoprotein MAC-1 subunit α; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b

Publications