NeuroMab™ Anti-KIR2DL1; KIR2DL2; KIR2DL3 Antibody, Clone 1-4F1

Product Overview

Description

1-4F1 is a monoclonal antibody which cross-reactive with KIR2DL1, -2, and -3.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Clone Number

1-4F1

Applications

FC; ELISA; Neut

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

KIR2DL1; KIR2DL2; KIR2DL3

Alternative Names

KIR2DL1; CD158A; KIR-K64; KIR221; NKAT; NKAT-1; NKAT1; p58.1; killer cell immunoglobulin like receptor; two Ig domains and long cytoplasmic tail 1; KIR2DS1; KIR2DL3

Product Pictures

FuncS

Figure 1 depicts the induction of NK-mediated killing by cross-reactive murine (DF200 and NKVSF1 (Pan2D)) and human (1-7F9, 1-4F1, 1-6F5, and 1-6F1) mAbs,

FuncS

Figure 2 depicts the induction of NK-mediated killing by the same antibodies as in Figure 5 . mAb induced (reconstituted) killing of KIR2DL1-expressing NK cells (YTS 30 KIR2DL1) by B-EBV cells expressing endogenous HLA-Cw4. E/T ratio = 2.30 pg/ml mAb.

Publications