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Creative Biolabs
Product

NeuroMab™ Anti-PVRIG BBB Shuttle Antibody, Clone NR01P

[CAT#: NRZP-1022-ZP2399]

Host Species:
Human
Species Reactivity:
Human
Applications:
WB; ELISA; Cyt; Block; Inhib; FC; In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Immunogen

Recombinant human PVRIG protein was generated in Compugen as the extra-cellular domain (ECD) of PVRIG fused to the Fc domain of human IgG1 (PVRIGHH).

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Clone Number

NR01P

Applications

WB; ELISA; Cyt; Block; Inhib; FC; In Vitro

Relevant Diseases

Tumor
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

PVRIG

Official Name

PVRIG

Full Name

Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein

Alternative Names

PVRIG; C7orf15; poliovirus receptor related immunoglobulin domain containing; CD112R; PVR related immunoglobulin domain containing
Publications

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For Research Use Only. Not For Clinical Use.
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