Product
Mouse Anti-MAPK9 / JNK2 Monoclonal Antibody (CBP1944)
[CAT#: NAB2007FY402]
Mouse Monoclonal [1A1] to MAPK9 / JNK2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-human MAPK9/JNK2 antibody recognizes mitogen-activated protein kinase 9, also known as Jun kinase, MAP kinase 9, c-Jun N-terminal kinase 2, c-Jun kinase 2, stress-activated protein kinase 1a and Stress-activated protein kinase JNK2.
Mitogen-activated protein kinase 9 is encoded by the MAPK9 (JNK2) gene and is a member of the MAP kinase family. MAP kinase acts as an integration point for a variety of biochemical signals and participates in a variety of cellular processes, such as proliferation, differentiation, transcriptional regulation and development. The kinase targets specific transcription factors to mediate early gene expression in response to various cellular stimuli. It is most related to MAPK8. MAPK8 is all related to cell apoptosis induced by ultraviolet radiation and is believed to be related to the cell death pathway mediated by cytochrome c. MAPK9 and MAPK8 are also called c-Jun N-terminal kinases. This kinase blocks the ubiquitination of the tumor suppressor p53, thus increasing the stability of p53 in non-stressed cells. Studies of the mouse counterpart of MAPK9 have shown that it plays a key role in T cell differentiation. Several transcript variants encoding alternative splicing of different isoforms have been reported (provided by RefSeq, September 2008).
Mouse anti-human MAPK9 antibody can detect a 54 kDa band. The antibody has been extensively validated by Western blot using whole cell lysates.
Mitogen-activated protein kinase 9 is encoded by the MAPK9 (JNK2) gene and is a member of the MAP kinase family. MAP kinase acts as an integration point for a variety of biochemical signals and participates in a variety of cellular processes, such as proliferation, differentiation, transcriptional regulation and development. The kinase targets specific transcription factors to mediate early gene expression in response to various cellular stimuli. It is most related to MAPK8. MAPK8 is all related to cell apoptosis induced by ultraviolet radiation and is believed to be related to the cell death pathway mediated by cytochrome c. MAPK9 and MAPK8 are also called c-Jun N-terminal kinases. This kinase blocks the ubiquitination of the tumor suppressor p53, thus increasing the stability of p53 in non-stressed cells. Studies of the mouse counterpart of MAPK9 have shown that it plays a key role in T cell differentiation. Several transcript variants encoding alternative splicing of different isoforms have been reported (provided by RefSeq, September 2008).
Mouse anti-human MAPK9 antibody can detect a 54 kDa band. The antibody has been extensively validated by Western blot using whole cell lysates.
Immunogen
Full-length recombinant human MAPK9 (NP_620707) produced in HEK293T cells
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1944
Applications
WB
Application Notes
WB (1/1000)
Relevant Diseases
Lou Gehring's Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS; 0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
1% Bovine Serum Albumin
50% Glycerol
Preservatives
Yes
Purification
Affinity chromatography from ascites.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
MAPK9/JNK2
Official Name
MAPK9
Full Name
Mitogen-Activated Protein Kinase 9
Alternative Names
Mitogen-Activated Protein Kinase 9; Stress-Activated Protein Kinase JNK2; Stress-Activated Protein Kinase 1a; C-Jun N-Terminal Kinase 2; MAP Kinase 9; EC 2.7.11.24; Jun Kinase; MAPK 9; JNK-55; SAPK1a; PRKM9
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
