Product
NeuroMab™ Anti-BACE1 Antibody, Clone 1D7
[CAT#: NRP-0422-P1007]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- Inhib; WB; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The antibody specifically binds to the human BACE1 protein, and can be useded for inhibiting amyloid-β formation and/or aggregation, inhibiting amyloid plaque formation, and treating neurodegenerative diseases.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Clone Number
1D7
Applications
Inhib; WB; In Vitro; In Vivo
Application Notes
BACE1
Product Properties
Preservatives
BSA Free
Concentration
1mg/mL
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
BACE1
Official Name
BACE1
Full Name
Beta-Secretase 1
Alternative Names
Beta-Secretase 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Beta-Site APP-Cleaving Enzyme; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE; ASP2;
Product Pictures
FuncS
Figure 1 shows the results of the GALR2 filtration assay.
Membrane preparations from A9 cells engineered to overexpress GALR2 were incubated with 125I-labeled human galanin and mouse anti-galanin hybridoma supernatants and harvested onto GF/B Unifilter plates. Twenty-one hybridomas were able to inhibit the binding of human galanin to GALR2.
FuncS
Figure 2 shows the results of the affinity assay.
FuncS
Figure 3 shows that administration of anti-galanin antibodies reduces tumor growth in established tumors.
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
Cell Assay Reagents
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
