Beta-Secretase (BACE1) Inhibitor Screening Kit (Fluorometric), Human
[CAT#: NK1120FY264]
The assay is sensitive, stable and high-throughput adaptable.
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
In the human β-secretase (BACE1) inhibitor screening kit for the determination of Genie, human BACE1 cleaves the BACE1 specific quenching substrate to produce a product with high fluorescence, which can be tested at Ex / Em = 435/500 Measured at nm. In the presence of a BACE1 inhibitor (control included in the kit), enzymatic cleavage is hindered and can be used to screen new inhibitor compounds.
Application Notes
Screening/characterizing/studying potential inhibitors of Human Beta-Secretase (BACE1)
Relevant Diseases
Alzheimer's Disease
Properites
Detection Method
Fluorescence (Ex/Em= 345/500 nm)
Assay Type
Inhibitor Screening Kit
Assay Time
Less than 1 hr
Preparation and Storage
Shipping
Gel Pack
Storage
-20°C
Handling Advices
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target Details
Target
BACE1
Official Name
BACE1
Full Name
Beta-Secretase 1
Alternative Names
Beta-Secretase 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Beta-Site APP-Cleaving Enzyme; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE; ASP2
Publications
Publications (0)
Kits
Neural Genes
Neural Antibodies
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Case Studies
For Research Use Only. Not For Clinical Use.
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