Human β-Secretase (BACE1) Inhibitor Screening Kit (Fluorometric), Human
[CAT#: NK1120FY221]
Highly Sensitive Assay for screening potential BACE1 inhibitors
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Lot Number
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Product Overview
Description
In our human β-secretase (BACE1) inhibitor screening kit, human BACE1 cleaves the particular quenching substrate of BACE1, producing a highly fluorescent product that can be quantified at Ex/Em = 435/500 nm. Enzymatic cleavage is inhibited in the presence of a BACE1 inhibitor (the kit contains a control), which can be used to screen for novel inhibitor compounds. The assay is high-throughput capable and can be finished in less than an hour.
Identifying and investigating possible inhibitors of Human β-Secretase (BACE1).
Identifying and investigating possible inhibitors of Human β-Secretase (BACE1).
Species Reactivity
Human
Application Notes
The assay is sensitive, stable and high-throughput adaptable.
Relevant Diseases
Alzheimer's Disease
Properites
Detection Method
Fluorescence (Ex/Em= 345/500 nm)
Preparation and Storage
Shipping
Dry Ice
Storage
-80°C
Research Use Only
For research use only
Target Details
Target
BACE1
Official Name
BACE1
Full Name
Beta-Secretase 1
Alternative Names
Beta-Secretase 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Beta-Site APP-Cleaving Enzyme; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE; ASP2
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
Cell Assay Reagents
For Research Use Only. Not For Clinical Use.
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