NeuroMab™ Anti-CD133 BBB Shuttle Antibody, Clone W6B3H10
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- FC; Cyt; ADCC; In Vitro
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 shows the effect of Fc-optimized chimeric antibodies chim293AClC3B9-SDIE (A) and chimW6B3H10-SDIE (B) and unstimulated human PBMC on cultured CD 133 expressing human WERI- Cell killing effect of Rbl cells and chimW6B3H10.
Figure 2 shows the cell killing effect of a chimeric antibody against NG2, which has been Fc-optimized at the same position as the above antibody, on human SKMel63-melanoma cells. Cytotoxicity was determined using a chromium release assay, indicating the duration of the assay and the target-effector ratio.
Figure 3 shows the binding of the CD133 antibody 293C3 (293AC1C3B9) to PBMCs of nine chronic lymphocytic leukemia (CLL) patients, as determined by flow cytometry.
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