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Creative Biolabs
Product

NeuroMab™ Anti-IFN Gamma BBB Shuttle Antibody,Clone NR2176P

[CAT#: NRZP-1022-ZP2817]

Host Species:
Human
Species Reactivity:
Human
Applications:
Block; Neut; Inhib; FC; In Vivo; In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Clone Number

NR2176P

Applications

Block; Neut; Inhib; FC; In Vivo; In Vitro

Relevant Diseases

Neuroinflammation
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

IFNGamma

Official Name

IFNG

Full Name

IFN gamma

Alternative Names

GD2
Product Pictures
FuncS

Figure 1 depicts the effect of inhibition of IFNγ-induced MHC class II expression in melanoma cells using scFv extracts.

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For Research Use Only. Not For Clinical Use.
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