NeuroMab™ Anti-SCN9A Antibody, Clone 1080
A functional antibody raised against Human, Mouse Nav1.7.
- Host Species:
- Rabbit
- Species Reactivity:
- Human; Mouse
- Applications:
- ELISA; Block; Inhib; In Vivo; In Vitro
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Low Endotoxin < 1 EU/mg
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Research Use Only
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Figure 1 shows that anti-Nav1.7 monoclonal antibody 1080 reduces the frequency of electrically induced DRG spikes in vitro.
983 mAb produces dose-dependent inhibition of Nav1.7 currents.
Figure 2 shows the automated patch clamp analysis of recombinant human Nav1.7 channels expressed in HEK cells. 1080 mAb produces dose-dependent inhibition of Nav1.7 currents.
983 mAb produces dose-dependent inhibition of Nav1.7 currents.
Figure 3 shows the automated patch clamp analysis of recombinant rat Nav1.7 channels expressed in HEK cells.
1080 mAb produced about 26% inhibition of Nav1.7 current at 25 μg/ml.
Figure 4 shows that antibody 1080 binds human and mouse domain B-loop El peptides.
1080 mAb produced about 26% inhibition of Nav1.7 current at 25 μg/ml.
Figure 5 shows ELISA data for antibody 1080 binding specifically to Nav 1.7 peptide.
1080 mAb produced about 26% inhibition of Nav1.7 current at 25 μg/ml.
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