NeuroMab™ Anti-SCN9A Antibody, Clone 932
A functional antibody raised against Human, Mouse Nav1.7.
- Host Species:
- Rabbit
- Species Reactivity:
- Human; Mouse
- Applications:
- ELISA; Block; Inhib; In Vivo; In Vitro
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Immunogen
Species Reactivity
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Host Species
Clone Number
Applications
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Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
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Research Use Only
Target
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Figure 1 shows that 932 and 983 anti-Nav1.7 mAbs reduce the frequency of electrically induced DRG spikes in vitro.
983 mAb produces dose-dependent inhibition of Nav1.7 currents.
Figure 2 shows that anti-Nav1.7 monoclonal antibody 932 reduces the frequency of electrically induced DRG spikes in vitro.
983 mAb produces dose-dependent inhibition of Nav1.7 currents.
Figure 3 shows the serum concentration-time profile of Antibody 932 in male Sprague Dawley rats following a single 10 mg/kg subcutaneous dose.
983 mAb produces dose-dependent inhibition of Nav1.7 currents.
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