Product
IonON™ Human Kv3.1 Recombinant Stable Cell Line
[CAT#: NCL-7P097]
Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.
- Species:
- Human
- Applications:
- Ion Channel Assay
- Cell Types:
- Ion Channel Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Fast-spike interneurons in the cortex and hippocampus, as well as neurons in the globus pallidus, are among the neurons that emit at high frequencies and are particularly abundant in Kv3.1. They enable channels containing Kv3.1 subunits to promote the rapid post-hyperpolarization period, thereby minimising recovery rate of sodium channel inactivation, and rapidly repolarize action potentials without affecting the threshold of action potential generation. Fast spikes in inhibitory neurons suffer damage as a result of pharmacological or genetic disruption of Kv3 currents, which also increases epilepsy susceptibility.
Cell Types
Ion Channel Cell
Applications
Ion Channel Assay
Application Notes
Electrophysiology assay (Conventional and automated patch clamp platforms)
Species
Human
Properties
Size
2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO
Mycoplasma Testing
The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details
Target
Kv3.1
Official Name
KCNC1
Full Name
Kv3.1
Alternative Names
Potassium Voltage-Gated Channel Subfamily C Member 1; Potassium Channel; Voltage Gated Shaw Related Subfamily C; Member 1; Voltage-Gated Potassium Channel Subunit Kv4; NGK2; Potassium Voltage-Gated Channel; Shaw-Related Subfamily; Member 1; Voltage-Gated Potassium Channel Protein KV3.1;
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
