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Creative Biolabs
Product

IonON™ Human Kv4.2/KChIP2 Recombinant Stable Cell Line

[CAT#: NCL-7P100]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
Ion Channel Assay
Cell Types:
Ion Channel Cell

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Product Overview

Description

In neurons (A current) and cardiomyocytes (Ito), the voltage-sensitive potassium channel hKv4.2/KCHiP2 quickly inactivates. They cause the initial repolarization of the cardiac action potential. The blocking of this channel may raise the risk of arrhythmia due to their critical involvement in regulating the trajectory of action potentials in diverse areas of the heart.

Cell Types

Ion Channel Cell

Applications

Ion Channel Assay

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

Kv4.2/KChIP2

Official Name

KCND2

Alternative Names

KCND2; KV4.2; RK5; potassium voltage-gated channel subfamily D member 2
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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