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NeuroMab™ Anti-HMG1 BBB Shuttle Antibody,Clone NR3746P
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- ELISA; Inhib; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 Binding kinetics and specificity of human anti-HMG1 antibodies.
HMG1 capture ELISA binding curves of several human anti-HMG1 antibodies demonstrate that these antibodies have different affinities for recombinant HMG1 produced in E. coli.
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP3157-1.png)
Figure 2 A number of human anti-HMG1 antibodies inhibited HMG1-stimulated cytokine release from human PBMCs.
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP3157-2.png)
Figure 3 Several human anti-HMG1 antibodies inhibit HMG1-stimulated cytokine gene expression in mouse macrophages (mMO).
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP3157-3.png)
Figure 4. A subset of human anti-HMG1 antibodies block the binding of recombinant HMG1 to RAGE.
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP3157-4.png)
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