Product
NeuroMab™ Anti-IGF1R Antibody, Clone 8
[CAT#: NRP-0422-P1436]
Functional antibody against Human, Cynomolgus Monkey, Marmoset Monkey IGF1R
- Host Species:
- Human
- Species Reactivity:
- Human; Cynomolgus Monkey; Marmoset Monkey
- Applications:
- ELISA; FC; Inhib; In Vivo; In Vitro
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The antibody binds to IGF-IR and inhibiting the binding of IGF-I and IGF-II to IG-RI.
Species Reactivity
Human; Cynomolgus Monkey; Marmoset Monkey
Clonality
Monoclonal
Host Species
Human
Isotype
IgG1
Clone Number
8
Applications
ELISA; FC; Inhib; In Vivo; In Vitro
Application Notes
WB: 0.2-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Unconjugated
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
IGF1R
Official Name
IGF1R
Full Name
insulin-like growth factor 1 (IGF-1) receptor
Alternative Names
IGF1R; CD221; IGFIR; IGFR; JTK13; insulin like growth factor 1 receptor; Insulin-like growth factor 1;IGF-1R
Product Pictures
FuncS
Figure 1 Primary tumor volumes measured during treatment up to day 55.
Vehicle: 1; Antibody 1A 20 mg/kg: 2; Antibody 1A 7 mg/kg: 3; Antibody 1A 2 mg/kg
Inhib
Figure 2 Inhibition of I125-IGF-I binding to HT29 cells by antibodies 1A, 8 and 23.
Inhib
Figure 3 The inhibitory effect of antibodies on the binding of I125-IGF-II to HT29 cells.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
